Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells |
FSD284 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000755 |
|
SpCas9 (Feldan Therapeutics) |
FSD284 |
Amphiphilic peptide |
McCray_CFTR_Cas9_Guide1 |
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|
Human |
Primary Airway Epithelia |
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|
|
2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
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|
RNP |
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|
Measured Values |
Samples Size: | 5 |
|
Mean |
5.3  |
1 |
8.85  |
2 |
6.99  |
3 |
5.23  |
4 |
2.51  |
5 |
2.91  |
| |
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