Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells |
FSD307 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000769 |
|
SpCas9 (Feldan Therapeutics) |
FSD307 |
Amphiphilic peptide |
McCray_CFTR_Cas9_Guide1 |
|
|
Human |
Primary Airway Epithelia |
|
|
|
2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
|
|
|
|
RNP |
|
|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
4.64  |
1 |
6.48  |
2 |
1.98  |
3 |
5.47  |
| |
|