Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells |
FSD197 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000857 |
|
AsCas12a (Feldan Therapeutics) |
FSD197 |
Amphiphilic peptide |
3849 45-5' |
|
|
Human |
Primary Airway Epithelia |
|
|
|
2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
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|
|
|
ribonucleoprotein (RNP) |
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Measured Values |
Samples Size: | 9 |
|
Mean |
21.41  |
1 |
39.2  |
2 |
35.4  |
3 |
28.3  |
4 |
11.95  |
5 |
19.54  |
6 |
12.14  |
7 |
11.75  |
8 |
12.579999923706  |
9 |
21.8249998092651  |
| |
|