Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells |
S10-MOD |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000944 |
|
AsCas12a (Feldan Therapeutics) |
S10-MOD |
Amphiphilic peptide |
3849 45-5' |
|
|
Human |
Primary Airway Epithelia |
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|
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2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
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ribonucleoprotein (RNP) |
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Measured Values |
Samples Size: | 3 |
|
Mean |
12.1  |
1 |
7.9  |
2 |
13.2  |
3 |
15.2  |
| |
|