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Gene Therapy Trial Report

Summary

A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration


NCTID NCT06765980 (View at clinicaltrials.gov)
Description
Development Status Active
Indication Geographic Atrophy Secondary to Age-related Macular Degeneration
Disease Ontology Term DOID:10871
Compound Name KRIYA-825
Compound Alias VV-14295
Sponsor Kriya Therapeutics, Inc.
Funder Type Industry
Recruitment Status
Enrollment Count 62 (ESTIMATED)
Results Posted Not Available

Therapy Information


Target Gene/Variant CR2-CR1
Therapy Type Gene transfer
Therapy Route In-vivo
Mechanism of Action Genetic delivery of therapeutic protein
Route of Administration Suprachoroidal
Drug Product Type Viral vector
Target Tissue/Cell
Delivery System Viral transduction
Vector Type AAV2
Editor Type
Dose 1 Undisclosed
Dose 2
Dose 3
Dose 4
Dose 5

Study Record Dates


Current Stage Phase1, Phase2
Submit Date 2024-12-19
Completion Date 2027-12-15
Last Update 2025-12-09

Participation Criteria


Eligible Age 55 Years - 80 Years
Standard Ages Adult, Older adult
Sexes Eligible for Study ALL

Locations


No.of Trial Sites 2
Locations New Zealand,Canada

Regulatory Information


Has US IND True
FDA Designations
Recent Updates

Resources/Links