Animal Reporter & Testing Centers

The initiative goal is to create and use new animal (mouse, pig, marmoset and rhesus macaque) reporter models to accelerate the translation of genome editing technologies into treatments for human diseases. The animal model systems are based on normal, non-diseased animals.

Rodent Testing Centers for Development of Reporter Systems and Evaluation of Somatic Cell Genome Editing Tools (U42 Clinical Trial Not Allowed) RFA-RM-18-012
PI Name	Institution Name	Title
HEANEY, JASON D (contact) DICKINSON, MARY E LAGOR, WILLIAM RAYMOND	BAYLOR COLLEGE OF MEDICINE	BCM-Rice resource for the analysis of somatic gene editing in mice
MURRAY, STEPHEN A (contact) LUTZ, CATHLEEN M	JACKSON LABORATORY	The Jackson Laboratory Gene Editing Testing Center (JAX-GETC)

Development of Large Animal Reporter Systems for Testing Somatic Cell Genome Editing Tools (U24 Clinical Trial Not Allowed) RFA-RM-18-013
PI Name	Institution Name	Title
CARLSON, DANIEL FRED	RECOMBINETICS, INC.	Development of Swine Reporter Models for Testing Somatic Cell Genome Editing Tools
FENG, GUOPING	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	Knockin marmoset reporters for non-invasive measuring of genome-editing efficiency
HENNEBOLD, JON D	OREGON HEALTH & SCIENCE UNIVERSITY	Rhesus Macaque Somatic Cell Gene Editing Resource

Large Animal Testing Centers for Evaluation of Somatic Cell Genome Editing Tools (U42 – Clinical Trial Not Allowed) RFA-RM-18-014
PI Name	Institution Name	Title
TARANTAL, ALICE F (contact) SEGAL, DAVID J	UNIVERSITY OF CALIFORNIA, DAVIS	Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools
WELLS, KEVIN (contact PRATHER, RANDALL	UNIVERSITY OF MISSOURI, COLUMBIA	Swine Somatic Cell Genome Editing (SCGE) Center