Upcoming Events

After two years, Cell Bio 2022 will return as an in-person meeting December 3-7, 2022, in Washington, DC. We are excited to make it possible for colleagues to reconnect face-to-face, while keeping health and safety paramount. We understand flexibility is also important. In addition to our in-person meeting, limited content will be available on-demand for purchase after the meeting so that all scientists can access the cutting-edge cell biology research that was presented during the in-person meeting.

Stem cells are moving toward the clinic as cellular therapeutics in several indications and are being tested in clinical trials in others. They are also employed to advantage in the discovery of novel therapeutics in several modalities, including physiologically relevant toxicity and drug screening platforms, and lend themselves to other treatment modalities, including gene therapy, and personalized precision medicine. The goal of this Cell Symposium is to bring together clinicians, academic researchers, and industry and regulatory stakeholders to discuss advances in the field and to champion new ideas to overcome the current challenges across the clinical and translational spectrum of stem–cell-based research and therapy.

The International Research Conference is a federated organization dedicated to bringing together a significant number of diverse scholarly events for presentation within the conference program. Events will run over a span of time during the conference depending on the number and length of the presentations. With its high quality, it provides an exceptional value for students, academics and industry researchers. International Conference on CRISPR and Gene Editing aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of CRISPR and Gene Editing. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of CRISPR and Gene Editing.

There have been tremendous advancements and breakthroughs in cell therapy treatments. Autologous treatments are extremely effective personalized therapies, but have significant medical, cost and commercialization limitations. Allogeneic treatments provide us with an opportunity to expand and extend access to personalized therapies to patients in need, but face efficacy, safety, and process hurdles. While related, the differences are stark, forcing your company to make unique and critical process and business decisions to ensure your company implements the best technologies to execute the most effective autologous and/or allogeneic cell therapy manufacturing strategy.

SAE Media Group's 15th Annual Pre-Filled Syringes and Injectable Drug Devices Conference will be bigger than ever, with a pre-conference focus day exploring the advances in PFS design for enhanced drug delivery proceeded by a two-day main conference comprising of morning keynote plenaries and parallel afternoon topic streams as detailed below: • Novel Drug Products and Large Volume Delivery • Sustainability for Injectable Delivery Devices • Primary Packaging Development • Connected Drug Delivery Devices

PepTalk connects protein science researchers from around the globe to share case studies, unpublished data, breakthroughs, and solutions that support and enhance biotherapeutics R&D. This year’s event will feature world-renowned speakers, cutting-edge technologies, and engaging networking events. Programming includes in-depth coverage of antibody discovery, protein engineering, bispecific antibodies, emerging immunotherapies, protein aggregation, machine learning, cell and gene therapy, protein expression, purification and production.

SAE’s 2nd annual Transdermal and Microneedle Drug Delivery conference will explore advances in microneedle diagnostics through case studies and real-world examples, whilst engaging in modern strategies for topical and transdermal drug delivery. The two-day agenda offers you peer-to-peer networking with CEO’s, Senior Vice presidents, Directors of Delivery Technologies, Heads of Product Development and many more. Key considerations for the conference will be transdermal and microneedle systems as a mode of therapeutic drug delivery in combination with optimization of device design and development. Vaccine delivery will a significant aspect of this year’s agenda with a focus on microneedle delivery technologies as a mode for vaccine delivery, in the pursuit to increase vaccine stability and accessibility. An outlook of the transdermal space will also be reviewed, including future directions and next steps required to advance the current field and accelerate access for patients and end users.

The inaugural Next Generation Ophthalmic Drug Delivery Summit is coming to San Francisco in January 2023, to help ophthalmic drug developers overcome translational challenges of developing novel long-lasting ophthalmic therapies via novel delivery methods to reduce healthcare burden and increase patient compliance. Join 21+ expert speakers from the likes of Genentech, Aerie Pharmaceuticals, Novartis, Clearside Biomedical, Janssen, Eyevensys, and EyePoint Pharmaceuticals to overcome your translational challenges and enhance extended drug efficacy while avoiding systemic and local adverse effects. Don’t miss your only opportunity for an industry-specific meeting for networking and sharing extended-duration therapies with the ophthalmic drug development community.

WELCOME BACK to the annual get-together for the entire genomics and biodata community, to discover, meet, learn and celebrate! This year's Festival will bring you inspirational speakers, the latest research and clinical breakthroughs, cutting-edge technology and incredible networking opportunities. Free for 90% of attendees, the Festival is designed to help you return to work armed with dozens of new ideas and contacts, but also to keep you engaged, excited and proud of the difference your efforts make for patients.  We can't wait to welcome you back in-person, for what promises to be our largest in-person and most vibrant Festival yet. Explore this year's agenda and speakers, find out what activities are taking place, and don't forget to register early as tickets are limited. 

In the past year alone, the field has learnt valuable lessons from the clinical trials and from the wider TGF-β field that will equip the immuno-oncology field with the knowledge needed to supercharge future TGF-β monotherapy or combinational therapeutics for precision medicine. From uncovering the effects and production of TGF-β in immune, tumor and stromal cells to exploring predictive and pharmacodynamic TGF-β biomarkers for patient identification and assessing the clinical challenges that led to recent clinical failures, the 3rd TGF-β for Immuno-Oncology Drug Development Summit is your one-stop-shop dedicated to harnessing you with the knowledge to unlock the potential of successfully targeting TGF-β. Tailored with 18+ senior leaders, the 2023 meeting will be taking place in-person for the first time - don't miss your chance to be in the room for your comprehensive guide on TGF-β in immuno-oncology! Whether you are new to this field or a seasoned expert, this meeting will provide you with the must-know takeaways from the basic biology to biomarkers to clinical trial design to overcome the clinical setbacks and produce a blockbuster TGF-β therapeutic.

Allogeneic approaches are deemed the future of cell therapy due to their potential to reduce costs, increase accessibility and enhance availability. However as clinical readouts emerge, challenges associated with limited durability, solid tumour targeting and therapy immunogenicity are hindering their efficacies. The Allogeneic Cell Therapies Summit Europe is returning in January to capture the clinical advances of European drug developers whilst addressing the specific challenges they face in development. These include European regulatory affairs, donor selection, scalable manufacturing and therapy persistence. With continued investment and growth in the allogeneic space, join European leaders from Gadeta, Antion Biosciences, TC BioPharm, and many more, as well as the US leaders undertaking European trials. This includes Atara Bio and Adicet Bio, as they progress development of multiple cell types to produce the next-generation of safe, effective and accessible cell therapies in Europe.

As cell & gene therapy and genomic medicine pipeline continues to mature, process development for viral vector is becoming critical for drug developers for the next phase, to deliver a quality, transformative cure to patients with affordability. The recent investments such as Novartis-Samsung Biologics $81m contract for viral vector manufacturing, Resilience raising $625m towards biomanufacturing capabilities including stable cell lines for viral vector production pave the foundation for scientific and technology innovations. With better understanding of these novel nanoparticles, developability and cell line development, the ability to optimize AAV, LV formulation and define robust CQAs are critical to drug developers’ ability to increase scalability with efficiency, reduce cost of goods and most importantly, ensure product quality control for patients.

The 5th Annual CRISPR AgBio Congress will unite research heads, molecular biologists, regulatory experts, and product developers who are involved in the journey from early R&D through to creating a marketable product. Perspectives will be shared from large Ag companies, innovative AgBiotechs, key academic groups, regulatory bodies, and independent institutions working to translate cutting-edge CRISPR technology into a tangible product.

#CGTI 2023 will highlight the manufacturing challenges facing Cell & Gene Therapy, bringing clear insights and industry best practices from renowned sector leaders. Achieve a deeper understanding of the many manufacturing and industrialization burdens unique to carrying durable and curative therapies to needy patients.

The Third International Summit on Human Genome Editing will take place on 6-8 March 2023 at the Francis Crick Institute, London UK. Building on previous events held in Washington, D.C. (2015) and Hong Kong (2018), this Summit will continue the important dialogue around human genome editing. It will facilitate a global discussion on somatic and germline genome editing, including developments in clinical trials and genome editing tools such as CRISPR/Cas9. Earlier this year a three-part series of online events Looking Ahead to the Third Human Genome Editing Summit discussed some of the key topics of the meeting. The three-day summit is being organized by the Royal Society, the UK Academy of Medical Sciences, the US National Academies of Sciences and Medicine and The World Academy of Sciences.

For almost 3 decades, the Molecular & Precision Med TRI-CON has served as the leading international meeting place for the diagnostics and precision medicine community. As we celebrate the 30th Anniversary and look forward to in-person networking, Cambridge Healthtech Institute once again takes the leadership role of bringing together the life science community at the TRI-CON 2023. Join thousands of international thought leaders to discuss the latest research, technologies, innovation and business models in implementing precision medicine, biomarkers and companion diagnostics, genomic medicine, and precision health; innovation and market access strategies for at-home diagnostics, point-of-care testing and molecular diagnostics for infectious diseases; liquid biopsy and advanced diagnostics for precision oncology, including Multi-Cancer Early Detection and Minimal Residual Disease testing; and emerging technologies for spatial biology and single-cell multiomics. The new track on Digital Medicine reflects the future of precision medicine and adds coverage of artificial intelligence, digital diagnostics and digital biomarkers, digital pathology, sensors and wearables. Join us in sunny San Diego for the in-person networking you’ve come to expect from the TRI-CON and special 30th Anniversary keynotes. Don’t miss a minute of the cutting-edge 10-track scientific program with convenient on-demand viewing.

The Bioprocessing Summit Europe brings together 500+ bioproduction, analytical and formulation professionals to advance the manufacture, quality and control of biological and genetic therapies. This 3-day, 10 track meeting has quickly become a premier meeting in the European bioprocessing calendar and is regarded by many as “the fastest growing bioprocessing meeting in Europe” following record growth in 2022 – 350 to 500+ attendees - and a sold out Exhibit Hall. We look forward to seeing you in Barcelona, or online, 14-16 March 2023, with expanded content on cell and gene therapy CMC and manufacturing, educational training seminars and a vastly bigger Exhibit Hall.

The RNA Editing GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

This meeting will bring together research that encompasses basic and translational virology. We envision this meeting showcasing the ubiquity of viruses while highlighting commonalities among researchers, from technology through a standard goal of understanding how viruses behave and adapt and how this may be exploited for prediction of the next outbreak or leveraged for therapeutic development. The scientific response to SARS-CoV-2/COVID-19 continues to showcase how science has progressed, as the rapidity of basic and translational research has been second to none, while also revealing our weaknesses as a population. This meeting is both a celebration of how far virology has come and a forecast of what is next and the inroads to get us there. Our topics will include: 1) Viruses within: defining the virome; interaction with the microbiome; endogenous retroviruses in health and disease; tools and technologies 2) Viral pathogens: evolution, genomics, spread, prediction, and pandemic preparedness of emerging and re-emerging viruses 3) Virus-host interaction: immunology, genetics, and host factors 4) Viruses as therapeutics: diagnostics, phage therapy, viral vectors, and disease therapy 5) Targeting viruses: antivirals, vaccines, antibodies: lessons from the past; successes versus failures

As the gene therapy field continues to break records, there are still significant challenges to overcome relating to safety, efficacy, and accessibility. The 6th Annual Gene Therapy for Rare Disorders 2023 Summit remains devoted to showcasing the top case studies and strategic learnings from the past year. With an expert speaking faculty devoted to bringing safer and more effective gene therapies to rare disease patients, key questions will be answered on how best the field can overcome regulatory, clinical, manufacturing and pricing bottlenecks to progress gene therapies into and through the clinic.

The International Research Conference is a federated organization dedicated to bringing together a significant number of diverse scholarly events for presentation within the conference program. Events will run over a span of time during the conference depending on the number and length of the presentations. With its high quality, it provides an exceptional value for students, academics and industry researchers. International Conference on Genetic Engineering and Genome Research aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Genetic Engineering and Genome Research. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Genetic Engineering and Genome Research.

The World Oncology Cell Therapy Congress (April 2023) is the only annual meeting bringing together drug developers, investors, solution providers and clinicians whose purpose is to deliver safe and effective adoptive cell therapy products to clinical implementation. Demonstrating the value of innovative cell therapy products and securing access for patients is a key priority for all developers. In 2023, the World OCT Summit will become the only industry forum to add an exclusive pre-event evening networking session for clinicians looking to overcome barriers to patient access and facilitate clinical distribution of transformative cell therapy products. The congress will also redefine industry networking, with every attendee incentivized to complete a profile, enabling everyone to find and touch base with the pioneers and companies they would like to meet. The congress schedule will also be revamped and be repositioned to reflect the dynamic research environment of the cell therapy field. Our on-stage talks, panels and Q&As will come under the following themes – ‘Breakthroughs and Pipeline Advancements’, ‘New Cell Therapy Platforms and Enabling Technologies’, ‘Manufacturing at Scale and Commercialization’ – and with our pre-event evening expanding into ‘Cell Therapy Access and Clinical Trial Delivery’.

This Cell Symposium aims to bring together thought leaders within these diverse fields, provide a forum for sharing and disseminating the latest advances, and provide a common ground for cross-disciplinary discussion and collaboration between the fields to understand the role of neural regulation in organismal homeostasis and disease. Topics: Brain-body communication in regulating appetite and consummatory behavior Brain-body interaction in regulating energy balance/thermoregulation The gut-brain axis and neuro-immune interactions in metabolic disease New technologies and models for studying brain-body communication and treatments of disease The influence of genes and lifestyle on energy homeostasis, metabolism, and mental health

Please join us for a special discussion on the development, manufacturing, and analysis of DNA & RNA therapeutics utilizing both cell-based and cell-free processes. This includes the raw materials necessary for in vitro replication and/or transcription with a focus on the acquisition of high-quality nucleotides and recombinant enzymes. The meeting will also consider drug product formulations and nanoparticle delivery systems, including the associated raw materials, with lipids as a particular focus.

Industry experts will share their knowledge and we will present and discuss how to optimize technologies and process setups, manufacturing challenges, and strategies such as digitalization, modelling, automation, scaling up, single-use technology, and securing process continuity. Case studies will also be presented in this track. Attend the cell and gene therapy track to learn about the future of cell and gene therapy bioprocessing. The track includes expert talks on the considerations around manufacturing ATMPs, from closed loop systems for cell therapy to decentralized sites. We also cover the technical aspects of how to optimize AAV manufacturing, tackling increased demand for viral and non-viral vectors, and developing the next generation of vectors.

The world’s largest gathering of protein engineering and biotherapeutics experts is back in Boston! PEGS Boston Summit is the leading biologics event with comprehensive programming covering all aspects of biologic drug development with in-depth presentations on protein and antibody engineering, immunotherapy, oncology, expression, analytics, immunogenicity, and more. Harness the power of in-person events, form genuine connections, create valuable relationships with peers, and become part of the PEGS community. We are currently recruiting speakers to assist in the development of the scientific programming, poster abstracts, and sponsorship & exhibit requests. Limited opportunities are available to present. Submit a presentation proposal by October 21 for priority consideration.

The International Research Conference is a federated organization dedicated to bringing together a significant number of diverse scholarly events for presentation within the conference program. Events will run over a span of time during the conference depending on the number and length of the presentations. With its high quality, it provides an exceptional value for students, academics and industry researchers. International Conference on DNA Structure and Genome Engineering aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of DNA Structure and Genome Engineering. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of DNA Structure and Genome Engineering.

The Bio-IT World Conference & Expo is the world’s premier event showcasing the technologies and analytic approaches that solve problems, accelerate science, and drive the future of precision medicine. For over 20 years, the Event has united a community of leading life sciences, pharmaceutical, clinical, healthcare, informatics, and technology experts in the fields of biomedical research, drug discovery & development, and healthcare from around the world. During May 16-18, 2023, the Bio-IT World Conference & Expo will return to the Hynes Convention Center in Boston (with a live virtual stream as well) and once again host the conversations that connect people, ideas, and opportunities that are advancing research and innovation. Join your peers for updates from inspiring keynotes, more than 190 presentations, and 3 days of interactive discussion. Let’s continue holding each other accountable for pushing the Bio-IT community forward!

The American Society of Gene and Cell Therapy’s (ASGCT) Annual Meeting is the premier event for professionals in gene and cell therapy. The five-day meeting is the best place for people in the field to learn from the latest scientific research, stay up to date on new technologies, and make career-advancing connections with peers. Originally designed as a venue for academic researchers to share their work, the Annual Meeting has grown to serve a wide community encompassing clinicians, bio-industry development, regulatory agencies, equipment manufacturers, patient advocates, and more.

The APS Annual Convention is the premier global event in psychological science, providing a forum to share scientific findings and ideas. The program features invited and submitted content from all areas of the field so you can find outstanding programs in your area of research, as well as from other areas that may be relevant to your work. Attend the APS Annual Convention to connect with researchers from around the world, renew acquaintances, and foster new collaborations.

The 4th Int'l Conference on Gene Editing and CRISPR Technologies (GECT 2023) will be held in Chengdu, China, during May 30-June 1, 2023. The aim of GECT is to provide a stage for researchers, engineers, academicians as well as industrial professionals from all over the world to present their research results and development activities in Biomedicine, Clinical Application of Gene Editing, CRISPR Systems and CRISPR Technologies, Effective Delivery for Genes in Vitro, Gene Knock In and Genomic Screening, Genome Engineering and DNA repair, Single Base Editing, etc. GECT 2023 will be a valuable and important platform for inspiring international and interdisciplinary exchange at the forefront of CGene Editing and CRISPR Technologies.

The Polymers GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. The conference will focus on both synthetic and biologically derived polymers and all aspects of their chemistry, including synthesis, structural characterization, and applications, with particular emphasis on new methods for polymer synthesis, sustainable polymer development, and innovative applications of polymers in medicine, energy, electronics, and advanced manufacturing.

International Conference on Animal Biotechnology and Gene Editing aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Animal Biotechnology and Gene Editing. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Animal Biotechnology and Gene Editing.

The International Research Conference is a federated organization dedicated to bringing together a significant number of diverse scholarly events for presentation within the conference program. Events will run over a span of time during the conference depending on the number and length of the presentations. With its high quality, it provides an exceptional value for students, academics and industry researchers. International Conference on Applications of Bacterial Genome Engineering aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Applications of Bacterial Genome Engineering. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields of Applications of Bacterial Genome Engineering.

The meeting will explore bacterial pathogens and pathogenesis from multiple perspectives, from cellular mechanisms to interbacterial interactions and community behavior, as well as pathogenesis in the complex milieu of the microbiota. The meeting will also highlight the pathogenic potential of the microbiome and explore microbiota-based and engineered antibacterial/therapeutic approaches. Our topics will include: Bacterial communication and signaling Interbacterial and interkingdom interactions Pathogen interactions with hosts and microbiomes Commensal homeostasis and dysbiosis Microbiome-based opportunities for therapy This innovative program will unite pathogenesis stalwarts with microbiome pioneers to share their collective knowledge—spanning molecules, microbes, and communities — to envision the future of infection biology research and therapeutic intervention.

The Histone and DNA Modifications GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

The Nucleic Acids GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

The Upconverting Nanoparticles GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. Upconverting nanoparticles (UCNPs) and related frequency-conversion nanomaterials find themselves at the intersection of many of today’s most important and demanding research areas including deep-tissue bio-imaging, sensing, and theranostics; solar light harvesting; neuroscience and optogenetics; nanoscale thermometry; and quantum communication. The rapidly emerging insights into fundamental – and tunable – upconverting nanomaterials properties together with fast-growing application spaces provides an exciting opportunity for the scientific exchange of unpublished data and provocative ideas that will ultimately maximize impact in the biomedical, information technology, and energy sectors. The 2023 GRC on Upconverting Nanoparticles brings together biologists, materials scientists, chemists, physicists, engineers, and theory and computational experts. It will accelerate progress and address the core challenges in this far-reaching research area, uniting world-renowned senior and junior experts. Participants will experience cutting-edge and thought-provoking invited lectures and engage in extensive scientific discussions and interaction with researchers, students, and postdoctoral fellows. Each lecture will be followed by ample time for lively discussion and question-and-answer sessions among invited speakers, discussion leaders, and all participants.

The Polyamines GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. This 2023 GRC/GRS will focus on the role of polyamines and polyamine-associated pathways in humans, animal models, microorganisms, and plants. Speaker sessions will feature topics on adult and pediatric cancers, medical genetics, aging, pathogens, and plants. Speakers have been chosen to highlight the most recent discoveries related to the biological roles of polyamines and the important clinical trials investigating polyamine-based targeting therapies for the treatment and prevention of cancer, genetic abnormalities, neurodegenerative disorders, and microbial pathogens.

The program will address the rapidly moving research on receptor-regulated calcium signaling and the critical questions that are key to establishing future therapies for cardiovascular, airway, gut, liver, immunoinflammatory, metabolic and neurological disorders. It is the only conference on this important topic that will be convened in 2023. Conference sessions will present the latest findings and promote discussion on: • Emerging new technologies to study calcium signaling • Organellar calcium signaling • Calcium signaling in metabolism and muscular and cardiovascular systems • Store operated calcium channels and TRP channels • Calcium signaling in cancer and the immune system • Calcium signaling in the nervous system • Calcium crosstalk with other signaling pathways • Calcium signaling proteins and regulatory mechanisms • New and notable session with latest breakthroughs The conference covers 11 sessions, 33 speakers, 16 junior investigator talks, and four poster sessions. The program includes two Career Development Workshops: one for postdocs and early career scientists about funding opportunities and how to write a successful grant; and a roundtable discussion with individuals from academia, industry, and publishing on the topic of career paths.

Retinal photoreceptor cells provide the critical first steps in vision, transducing incident photons into changes in membrane potential relayed via neural circuits to higher visual centers. Research on photoreceptors and their supporting epithelium, the retinal pigment epithelium (RPE), is not only essential for understanding how we see, but it has also advanced knowledge in areas such as G protein signaling, neurophysiology, and protein structure and function. In addition, fundamental photoreceptor and RPE research has been essential for new insights in the pathobiology of vision loss; blinding diseases like retinitis pigmentosa and macular degeneration result from photoreceptor degeneration that typically first appears as defects in cell biological and physiological mechanisms of the photoreceptors and/or the adjacent RPE.

The 2023 Advancing Gene Therapy conference will be held in The Westin Walthum, MA. The meeting will provide conference attendees updates on recent gene therapy innovations from vector designs to product launch. Drivers of these advances will be discussed including the rapid pace of change from biotechnology, pharmaceutical, manufacturing and CROs with preclinical, non-clinical and trial expertise. In addition, the summit covers emerging and related fields including Gene Editing & CRISPR, Cell Therapies, Gene Therapy for Cancer, Immunotherapy, Rare diseases, Blood Disorders, Neurological Disorders, Toxicology Studies, advances in manufacturing, regulatory and medical affairs, Commercialization Strategies, Business Models and Market Access.

The scientific program will cover various aspects of CRISPR biology ranging from genetics, biochemistry, structural biology, ecology, evolution and applications. The scientific part of the meeting is planned for June 28 to 30. We hope to welcome you in Würzburg June 27 at the evening reception. A group activity is being planned for July 1.