ASGCT 2023 Meeting at a Glance
May 16-20, 2023 | Los Angeles, CA
The American Society of Gene and Cell Therapy’s (ASGCT) Annual Meeting is the premier event for gene and cell therapy professionals. It’s the best place for people in the field to learn from the latest scientific research and stay up to date on new technologies. In 2023, many SCGE researchers attended a week of workshops, poster sessions, oral abstracts, and scientific symposiums.
SCGE Scientific Symposium
Friday, May 19th | 10:15 AM – 12:00 PM | West Hall B
This symposium highlighted some of the most exciting science and successful facets of program design of the SCGE program. This session demonstrated the facets of this program that are quintessential to all Common Fund programs: it’s transformative, catalytic, synergistic, cross-cutting, and unique features. The proposed speakers were selected for their unparalleled expertise, deep engagement with the SCGE program opportunities, and the broad relevance of their anticipated presentation to the ASGCT membership.
Session Details
Speaker | Symposium Topic | Time |
---|---|---|
Felicia Qashu, PhD, NIH/OD | SCGE Initiatives Introduction | 10:15 AM |
Charles A. Gersbach, PhD, Duke University | Technologies to Facilitate Translation of Somatic Cell Editing | 10:30 AM |
Ross Wilson, PhD, University of California Berkeley | Delivery Initiative Highlights | 10:45 AM |
Shunqing Liang, PhD, University of Massachusetts Medical School | Develop combinatorial non-viral and viral CRISPR delivery for lung diseases | 11:00 AM |
Cathleen Lutz, PhD, The Jackson Laboratory | Animal Initiative Highlights | 11:15 AM |
Bruce R. Conklin, MD, Gladstone Institute of Cardiovascular Medicine | Biological Initiative Highlight | 11:30 AM |
Marrah Lachowicz-Scroggins, PhD, NIH/NHLBI | Phase 2 of the NIH's Somatic Cell Genome Editing Program | 11:45 AM |
SCGE Member Abstracts
Wednesday, May 17th
Presenter | Abstract Title | Category | Session Title | Time | Location |
---|---|---|---|---|---|
Kathy Snow | Development and Characterization of New Reporter Mouse Models for In Vivo Gene Editing | Poster Session | Wednesday Poster Session | 12:00 PM | Poster #504 |
Karthikeyan Ponnienselvan | Reducing the Inherent Auto-Inhibitory Interaction within the pegRNA Enhances Prime Editing Efficiency | Poster Session | Wednesday Poster Session | 12:00 PM | Poster #523 |
Samantha Maragh | Outcomes from the First NIST Genome Editing Consortium Interlab Study | Poster Session | Wednesday Poster Session | 12:00 PM | Poster #533 |
Nicole Paulk | AAV Immuno-Gene Therapy Delivers Vectorized Cytokines to Effectively Treat High-Grade Gliomas | Oral Abstract Session | Preclinical and Proof-of-Concept In Vivo Studies I | 3:45 PM | Room 408 AB |
Cicera Lazzarotto | CHANGE-seq-BE Enables Sensitive and Unbiased Genome-Wide Profiling of Adenine Base Editors In Vitro | Oral Abstract Session | Genome Editing Therapies & Safety I | 4:15 PM | Room 515 AB |
Alice Tarantal | Monitoring Fetal and Infant Somatic Cell Genome Editing in Rhesus Monkeys with Total-Body PET | Oral Abstract Session | AAV Vectors: Clinical and Non-Human Primate Studies | 4:30 PM | Room 411 |
Alice Tarantal | AAV Serotype Tropism and Editing in Young Rhesus Monkeys | Oral Abstract Session | AAV Vectors: Clinical and Non-Human Primate Studies | 4:45 PM | Room 411 |
Wan Du | Shuttle Peptides-Mediated Local RNP Delivery of Editing Complex in the Sensory Organs of the Inner Ear and Retina In Vivo in Adult Mice | Oral Abstract Session | Synthetic/Molecular Conjugates and Physical Methods for Delivery of Gene Therapeutics I | 4:45 PM | Petree Hall C |
Thursday, May 18th
Friday, May 19th
Presenter | Abstract Title | Category | Session Title | Time | Location |
---|---|---|---|---|---|
Benjamin Deverman | Engineering AAVs to Target and Cross the Brain Vasculature | Scientific Symposium | New Approaches in Cell and Gene Therapy for Cardiovascular Disease | 9:15 AM | Room 411 |
Marrah Lachowicz-Scroggins and Felicia Qashu | Introduction to SCGE Consortium | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 10:15 AM | West Hall B |
Charles Gersbach | Technologies to Facilitate Translation of Somatic Cell Editing | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 10:30 AM | West Hall B |
Ross Wilson | Delivery Initiative Highlights (SCGE Consortium) | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 10:45 AM | West Hall B |
Shunqing Liang | Develop combinatorial non-viral and viral CRISPR delivery for lung diseases (SCGE Consortium) | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 10:45 AM | West Hall B |
Cathleen Lutz | Animal Initiative Highlight | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 11:15 AM | West Hall B |
Bruce Conklin | Biological Initiative Highlight | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 11:30 AM | West Hall B |
Marrah Lachowicz-Scroggins | Phase 2 of the NIH's Somatic Cell Genome Editing Program | Scientific Symposium | Somatic Cell Genome Editing (SCGE) Program | 11:45 AM | West Hall B |
Chris Walkey | A Multi-Dimensional Survey of AAV Tropism in Mice | Poster Session | Friday Poster Session | 12:00 PM | Poster #1409 |
John Kelly | Development of a Highly Efficient Modular and Multiplexed CRISPR Editing System for Multimodal Tracking of CAR-T Cells | Poster Session | Friday Poster Session | 12:00 PM | Poster #1502 |
Scot Wolfe | Enhancing CRISPR Genome Editing by Extensive Chemical Modification and Self-Delivery of Guide RNAs | Poster Session | Friday Poster Session | 12:00 PM | Poster #1507 |
Alice Tarantal | Translational Programs in Gene Therapy and Somatic Cell Genome Editing: Nonhuman Primate Research Opportunities | Poster Session | Friday Poster Session | 12:00 PM | Poster #1545 |
Bikash Pattnaik | Validating Reliability of Genome Editing Using Ion Channels as Drug Target | Poster Session | Friday Poster Session | 12:00 PM | Poster #1619 |
Kirstan Gimse | Transcriptomic Profiling of the Mouse Hippocampus After Intracerebral Injection of Cas9 Nanocapsule Genome Editors | Poster Session | Friday Poster Session | 12:00 PM | Poster #1653 |
Madalena Castro | Peptide-Mediated Delivery of CRISPR Ribonucleoprotein (RNP) into Primary Human CD34+ Hematopoietic Stem Cells | Poster Session | Friday Poster Session | 12:00 PM | Poster #1687 |
Cathleen Lutz | Optimizing Base Editing Strategies in a Mouse Model of Zellweger Syndrome | Oral Abstract Session | AAV Vectors - Preclinical and Proof-of-Concept In vivo Studies I | 4:30 PM | Room 408 AB |
Varun Katta | Optimization and Characterization of Genome Editing of Human Hematopoietic Stem Cells to Induce Fetal Hemoglobin towards SAGES-1 Clinical Trial | Oral Abstract Session | Gene Targeting and Gene Correction: Hemoglobin, Muscle, and Eye | 5:00 PM | Room 515 AB |
Saturday, May 20th
Presenter | Abstract Title | Category | Session Title | Time | Location |
---|---|---|---|---|---|
Joseph Muldoon | Efficient and Minimally Perturbative CAR-T Cell Engineering Using Peptide-Enabled CRISPR RNP Delivery | Oral Abstract Session | Cell Therapy Product Manufacturing | 8:00 AM | Petree Hall D |
Alan Rosales | Evolving Nephrotropic AAV Variants Using Ex Vivo NHP Kidney Perfusion and Human Kidney Organoids | Oral Abstract Session | AAV Development for Eye, Muscle, Kidney and CNS | 9:15 AM | Concourse Hall 150 & 151 |
Alexandra Piotrowski-Daspit | Polymeric nanoparticle strategies to restore CFTR function | Scientific Symposium | Strategies to Deliver Genetic Therapies for Cystic Fibrosis | 11:15 AM | Room 502 AB |