YearTitleCollaborators
2019-2020Evaluation of LNP-based nanoparticles for systematic delivery of base editorsPeter Glazer, MD PhD, Yale University
W. Mark Saltzman, PhD, Yale University
Alice Tarantal, PhD, University of California at Davis
2019-2020Improved reporters to evaluate base editor activity in miceSteve Murray, PhD, Jackson Laboratory
David Liu, PhD, Broad Institute
2019-2020Development of a GFP-IVS2 Mouse Reporter Strain for PNA-based Genome Editing DetectionSteve Murray, PhD, Jackson Laboratory
Peter Glazer, MD PhD, Yale University
2019-2020Nanoparticles delivery of new Cas enzymesNiren Murthy, PhD, University of California Berkeley
Jennifer Doudna, PhD, University of California Berkeley
2019-2020Comparing the efficiency and cellular impact of non-viral, hepatocyte-targeted delivery vehicles with viral-mediated gene delivery in a microphysiological liver on chip platformSamira Kiani, PhD, University of Pittsburgh
Shaoqin Gong, PhD, University of Wisconsin-Madison
Ross Wilson, PhD, University of California Berkeley
2019-2020Non-enzymatic gene editing of hematopoietic cells in utero in nonhuman primates by next generation PNA nanoparticlesZheng-Yi Chen, PhD, Massachusetts Eye and Ear Infirmary
Qiaobing Xu, PhD, Tufts University
David Liu, PhD, Broad Institute
2019-2020Adenine Base Editor Ribonucleoprotein Delivery to Primary Airway Epithelia using Amphiphilic PeptidsPaul McCray, MD, University of Iowa
Alice Tarantal, PhD, University of California at Davis
David Liu, PhD, Broad Institute
David Guay, PhD, Feldan Institute
2019-2020RNP delivery platforms for biodistribution of genome editors to human neural microtissuesTodd McDevitt, PhD, Gladstone Institute
Ross Wilson, PhD, University of California Berkeley
2020-2021Guide Engineering to Enhance the Safety and Efficacy of Base Editing in vivoErik Sontheimer, PhD, University of Massachusetts Medical School
David Liu, PhD, Broad Institute
2020-2021Development of a single AAV vector CRISPR-CasĪ¦ platform technologyJennifer Doudna, PhD, University of California Berkeley
David Liu, PhD, Broad Institute
Ben Deverman, PhD, Broad Institute
2020-2021Novel virus-like particles (VLPs) for precise delivery of base-editors in iPSC disease modelsBruce Conklin, MD, Gladstone Institute
Jennifer Doudna, PhD, University of California Berkeley
2020-2021Cas9 ribonucleoprotein delivery targeted to kidney epitheliumRoss Wilson, PhD, University of California Berkeley
Benjamin Freedman, PhD, University of Washington
2020-2021Developing methods for unbiased off-target genome editing analysis in vivoScot Wolfe, PhD, University of Massachusetts Medical School
Wen Xue, PhD, University of Massachusetts Medical School
2020-2021Improving Split AAV9 Base Editors In MiceCathleen Lutz, PhD, Jackson Laboratory
David Liu, PhD, Broad Institute
2020-2021CEST based imaging of Cas9-b-lactamase fusion proteinsNiren Murthy, PhD, University of California Berkeley
Moriel Vandsburger, PhD, University of California Berkeley