Meet the Researcher: Claire Clelland

Claire Clelland, MD, PhD

Claire Clelland, MD, PhD is a physician-scientist at the University of California, San Francisco. She is a co-investigator on the SCGE project “Correction of Neurological Disease via Allele Specific Excision of Pathogenic Repeats” led by Dr. Jennifer Doudna. In this interview, Dr. Clelland sat down to talk more about her project and how she keeps patients and health equity at the heart of her research.

SCGE Phase 2 Publications with Dr. Clelland

• Validated assays for the quantification of C9orf72 human pathology
• Building CRISPR Gene Therapies for the Central Nervous System: A Review
• Reversal of C9orf72 mutation-induced transcriptional dysregulation and pathology in cultured human neurons by allele-specific excision
• Zfp106 binds to G-quadruplex RNAs and inhibits RAN translation and formation of RNA foci caused by G4C2 repeats