Events for April 27, 2024 - April 27, 2024

The Polyamines GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field. This 2023 GRC/GRS will focus on the role of polyamines and polyamine-associated pathways in humans, animal models, microorganisms, and plants. Speaker sessions will feature topics on adult and pediatric cancers, medical genetics, aging, pathogens, and plants. Speakers have been chosen to highlight the most recent discoveries related to the biological roles of polyamines and the important clinical trials investigating polyamine-based targeting therapies for the treatment and prevention of cancer, genetic abnormalities, neurodegenerative disorders, and microbial pathogens.

The program will address the rapidly moving research on receptor-regulated calcium signaling and the critical questions that are key to establishing future therapies for cardiovascular, airway, gut, liver, immunoinflammatory, metabolic and neurological disorders. It is the only conference on this important topic that will be convened in 2023. Conference sessions will present the latest findings and promote discussion on: • Emerging new technologies to study calcium signaling • Organellar calcium signaling • Calcium signaling in metabolism and muscular and cardiovascular systems • Store operated calcium channels and TRP channels • Calcium signaling in cancer and the immune system • Calcium signaling in the nervous system • Calcium crosstalk with other signaling pathways • Calcium signaling proteins and regulatory mechanisms • New and notable session with latest breakthroughs The conference covers 11 sessions, 33 speakers, 16 junior investigator talks, and four poster sessions. The program includes two Career Development Workshops: one for postdocs and early career scientists about funding opportunities and how to write a successful grant; and a roundtable discussion with individuals from academia, industry, and publishing on the topic of career paths.

Retinal photoreceptor cells provide the critical first steps in vision, transducing incident photons into changes in membrane potential relayed via neural circuits to higher visual centers. Research on photoreceptors and their supporting epithelium, the retinal pigment epithelium (RPE), is not only essential for understanding how we see, but it has also advanced knowledge in areas such as G protein signaling, neurophysiology, and protein structure and function. In addition, fundamental photoreceptor and RPE research has been essential for new insights in the pathobiology of vision loss; blinding diseases like retinitis pigmentosa and macular degeneration result from photoreceptor degeneration that typically first appears as defects in cell biological and physiological mechanisms of the photoreceptors and/or the adjacent RPE.

The 2023 Advancing Gene Therapy conference will be held in The Westin Walthum, MA. The meeting will provide conference attendees updates on recent gene therapy innovations from vector designs to product launch. Drivers of these advances will be discussed including the rapid pace of change from biotechnology, pharmaceutical, manufacturing and CROs with preclinical, non-clinical and trial expertise. In addition, the summit covers emerging and related fields including Gene Editing & CRISPR, Cell Therapies, Gene Therapy for Cancer, Immunotherapy, Rare diseases, Blood Disorders, Neurological Disorders, Toxicology Studies, advances in manufacturing, regulatory and medical affairs, Commercialization Strategies, Business Models and Market Access.

The scientific program will cover various aspects of CRISPR biology ranging from genetics, biochemistry, structural biology, ecology, evolution and applications. The scientific part of the meeting is planned for June 28 to 30. We hope to welcome you in Würzburg June 27 at the evening reception. A group activity is being planned for July 1.

The CMC Strategy Forum is the premier scientific meeting that brings together regulatory, industry, and academic professionals to discuss key emerging CMC issues that affect biotechnology in an open and transparent workshop format.

Overcome regulatory hurdles across non-clinical, clinical & CMC functions from pre-IND through to approval and satisfy regulatory requirements for gene therapies by demonstrating safety & efficacy

The WCBP Symposium is known as the highest-regarded annual conference addressing the role of current and emerging CMC analytical technology among evolving US and international regulatory perspectives. Hear from and engage with leaders on a wide range of topics including CMC development strategies, innovative analytical characterization, global submission strategies, next-generation therapeutics & vaccines, as well as the challenges and promises of CRISPR-based therapeutics. This year, WCBP will be co-sponsored by the US FDA.

The largest and original forum for precision medicine. PMWC provides an exceptional forum for the exchange of information about the latest advances in technology, clinical implementation, research, and in all aspects related to the regulatory and reimbursement sectors.

In this free virtual event, Genetic Engineering and Biotechnology News [...]

The Gene Therapy Comparability Summit will ensure that you can establish comparability in your clinical phase of development and prove to regulators that your products are comparable when scaling up for commercialization and navigating process changes.

Rare Disease Day at NIH aims to raise awareness about rare diseases, the people they affect, and NIH collaborations that address scientific challenges and advance research for new treatments.

TAGC is a unique conference organized by the Genetics Society of America that offers innovative sessions that get to the heart of our shared research interests. The diverse and interdisciplinary scope of TAGC 2024 allows researchers to discover answers and explore new directions in today’s genetics and genomics research.

The 18th conference on rare disease combines recent research on genetic mechanisms involved in disease, with advances in approaches for clinical care. This year’s conference will include discussions on the use of a ‘pangenome’ to improve diagnostic yield, the role of common variants in rare disease, and new developments in prenatal and neonatal genomic screening.

Join pioneers from Commercial, Marketing, Medical Affairs, RWE, Market Access, Patient Engagement, and key stakeholders, will come together to deliver value to overcome the challenges that threaten the future viability of innovation.

Bringing together key figures from industry, regulatory bodies, patient non-profits, payers, and key service providers, this is the field’s foremost meeting for collectively progressing rare gene therapy programs into and through the clinic. 

The 4th Gene Therapy for Muscular Disorders Summit in April will focus on gene therapies for muscular disorders to tackle the most pressing challenges and together, seek solutions to realize these novel therapeutic potentials for patients in need.

The 5th CRISPR and Beyond conference provides a forum for biomedical researchers from academia and industry working on high throughput screening, genome engineering, and variant effect interpretation to discuss perturbations at scale to understand genomes.

Meet the European CRISPR Medicine and Genomic Medicine community to discuss tools, delivery, safety, functional genomics, standards and regulations, and more. 

The RARE Drug Development Symposium, hosted by Global Genes and the Orphan Disease Center of the University of Pennsylvania, equips advocates with the knowledge, skills and connections they need to advance therapy development for their communities.

The American Society of Gene and Cell Therapy’s (ASGCT) Annual Meeting is the premier event for professionals in gene and cell therapy to learn from the latest scientific research, stay up to date on new technologies, and make career-advancing connections with peers.

This in-person and virtual public workshop will bring together rare disease patient advocates, academic researchers, regulated industry, and other key stakeholders to discuss considerations for the use of natural history study and registry data in rare disease drug development programs.

Address obstacles at each stage of translation and progress the future of cell and gene therapies to bring scientific innovation to therapeutic reality for patients worldwide.

Join 80+ patient advocacy and engagement professionals at gene therapy companies and patient advocacy groups to gain actionable insights that you can immediately implement into your own gene therapy programs, and come together with the community to develop solutions to the challenges that are unique to the gene therapy space.

In The State of CRISPR and Gene Editing virtual summit, GEN proudly gathers a tantalizing line-up of luminaries from academia and industry to discuss the latest research developments, innovations, and advanced technologies that are expanding the CRISPR toolbox, delivering new therapies to patients and safeguarding our food supply.

The Cell and Gene Therapy Products (CGTP) Symposium: Manufacturing, Quality and Regulatory Considerations enables the exchange of scientific ideas and dialogue with regulators that form the basis of evolving regulatory practices in the development of these diverse and innovative products.

This event will focus on finding and optimizing novel vectors to increase specificity, target new cell types, expand packaging capacities, and reduce toxicity risks to create safer, cost-effective and efficacious gene therapies. 

The conference seeks to present the latest research findings in these fields and support early-career investigators, women, and other historically-excluded groups in the field of genome editing.

Learn more about RNA Therapeutics from concept to clinic from leaders across the field, including SCGE PI's Jennifer Doudna, Kiran Musunuru, and Sonia Vallabh. 

The International Summit on Cell and Gene Therapy serves as a platform to explore the fundamental concepts of these transformative therapies. The summit brings together experts from academia and industry to discuss a range of topics related to cell and gene therapy, including ethical considerations, social implications, tools, techniques, marketing strategies, and the commercialization of cell and gene therapy products. It also showcases the latest research progress in CGT and explores opportunities for further enhancements in availability and productivity of these therapies.

The specific goal for this meeting is to foster fruitful and creative interactions between researchers interested in applying these systems to genome engineering and related advances in a wide variety of organisms, together with scientists studying the basic biology of CRISPR-Cas and related bacterial defense systems.

Week in RARE, presented by Global Genes, features the RARE Health Equity Forum and the RARE Advocacy Summit.