Testing virus region 4 (VR4) mutant cross-species compatible Adeno Associated Viruses (ccAAVs) in mice. |
AAV9-mCherry |
Relative neuronal transduction levels were quantified by counting the number of transduced neurons, identified based on morphology, for each brain region per 50um sagittal section |
striatum |
astrocyte |
Delivery Efficiency |
15000000356 |
|
|
|
|
|
AAV9-mCherry; |
|
Mouse |
C57BL/6 |
|
intravenous |
|
5e13Â vg/kg |
once |
|
200 microliters |
4 weeks |
AAV vector encoded |
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|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
46.83  |
1 |
38  |
2 |
37  |
3 |
65.5  |
| |
|
Representative image of AAV9-mCherry delivery in brain striatum. Neuronal and astrocytic expression were visualized by immunohistochemical staining. |
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