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3849 45-5' Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
3849 C>T loci Guide - [In Vitro] [Collaborative Opportunity Fund] [Human] Matched Fields: category : Guide Show Experiments (1) Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
AAVS1_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_10 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_11 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_12 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_13 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_14 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets AAVS1 safe harbor locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
ABE8e-Cas12a Guide 1 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 10 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 11 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 2 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 3 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 4 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 5 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 6 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 7 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 8 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas12a Guide 9 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
ABE8e-Cas9 Guide 1 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 10 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 2 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 3 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 4 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 5 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 6 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 7 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 8 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
ABE8e-Cas9 Guide 9 CCR5 Rhesus Guide - [In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Ai14 gRNA Guide - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Show Experiments (2) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
Ai9 SaCas9 Guide A Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Ai9 SaCas9 Guide B Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
B2M Guide - [In Vitro] [Collaborative Opportunity Fund] [Human] Matched Fields: category : Guide Show Experiments (1) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
B2M_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
BCM_ssAAV5-Sa_sgB Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgA Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgB Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
CBLB_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_11 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_13 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_14 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_15 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_16 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_10 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_11 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_12 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_13 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_10 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_11 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Cas12j-GFP1 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP1 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP11 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP12 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP13 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP15 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP16 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP17 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP18 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP19 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP20 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP21 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP22 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP23 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Guide targeting eGFP compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Cas9-CFTR-R553X Guide - [In Vitro] [Collaborative Opportunity Fund] [Human] Matched Fields: category : Guide CFTR-R553X Show Experiments (1) Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells
DMD low gRNA-1 Guide - [In Vitro] [Biological Effects Initiative] [Human] Matched Fields: category : Guide One of two low-off target gRNAs delivred by dual gRNA AAV vector pAAV[2gRNA]-mCherry-U6>{SagRNA#1*}:{SagRNA#2} Show Experiments (1) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids.
DMD low gRNA-2 Guide - [In Vitro] [Biological Effects Initiative] [Human] Matched Fields: category : Guide One of two low-off target gRNAs delivred by dual gRNA AAV vector AAV-gRNA Show Experiments (2) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
FAS_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
GER10-ABE-REV Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide sgRNA target sequence for A base editor in Venus Show Experiments (1) Validating Gene Editing Reporter 10 (GER10) Mouse Model in Heterozygous Blastocysts
GER12-g1-FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Gene Editing Reporter 12 (GER12) Mouse Model in Heterozygous Blastocysts
GER12-g2-FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Gene Editing Reporter 12 (GER12) Mouse Model in Heterozygous Blastocysts
GER14-g1-Cpf1-FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
GER14-g1-SaC9-FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
GER14-g1-SpC9-FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
GER18/19 gRNA2 FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide 5' guide flanking IVS2-654 C>T mutation Show Experiments (2) Validating Gene Editing Reporter 18 (GER18) Mouse Model in Heterozygous Blastocysts Validating Gene Editing Reporter 19 (GER19) Mouse Model in Heterozygous Blastocysts
GER18/19 gRNA3 FWD Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide 3' guide flanking IVS2-654 C>T mutation Show Experiments (2) Validating Gene Editing Reporter 18 (GER18) Mouse Model in Heterozygous Blastocysts Validating Gene Editing Reporter 19 (GER19) Mouse Model in Heterozygous Blastocysts
L1-modified Guide - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (3) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L1-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L2-modified Guide - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (2) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L2-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-modifed Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
LAG3_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_10 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
McCray_CFTR_Cas9_Guide1 Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
NKG2A Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide gRNA targeting human NKG2A exon 3 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells.
Negative control gRNA Guide - [In Vitro] [Collaborative Opportunity Fund] [Human] Matched Fields: category : Guide Negative control guide RNA avoid any targets in human/mouse/rat Show Experiments (2) Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system
Negative control gRNA Guide - [In Vitro] [Collaborative Opportunity Fund] [Human] Matched Fields: category : Guide Negative control guide RNA avoid any targets in human/mouse/rat Show Experiments (1) Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
PDCD1_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_10 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_11 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_12 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_13 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_14 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_15 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_16 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_06 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_07 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_08 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_09 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Pcsk9 Exon 1 splice domain Guide - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Pcsk9 Exon 1 splice domain Show Experiments (2) Pcsk9 adenine base editor efficiency in liver and nonliver tissue Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver
R1-modified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R1-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-modified Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (2) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R26-1 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
R26-2 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
R26-3 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
R26-52 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
R26-59 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
R26-69 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
STS118 (TLR-MCV1a; Sp_t2-PS:Sp_c20_TLR_MCV1a) Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets traffic light reporter transgene, CY3 labeled Show Experiments (1) Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain
STS118 (TLR-MCV1a; Sp_t2:Sp_c20_TLR_MCV1a) Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS119 (TLR-MCV1b; Sp_t2:Sp_c20_TLR_MCV1b) Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS120 (TLR1; Sp_t2:Sp_c20_TLR1) Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide Targets traffic light reporter transgene Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR1 reporter in human cells
STS134 (PCSK9b; Sp_t2:Sp_c20_PCSK9b) Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS135 (PCSK9c; Sp_t2:Sp_c20_PCSK9c) Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS159 (mTmG; Sp_t2-PS:Sp_c0_mTmG) Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2-PS:Sp_c20_mTmG) Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c0_mTmG) Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c20_mTmG) Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (3) Testing newly chemically modified crRNA and tracrRNA in mTmG mouse embryonic fibroblasts Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center
STS204 (DNMT1; Sp_t2:Sp_c20_Dnmt1) Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide For endogenous locus Show Experiments (1) Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center
STS204 (DNMT1; Sp_t41:Sp_c20_Dnmt1) Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS205 (BACE1; Sp_t41:Sp_c20_Bace1) Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS96 (PCSK9a; Sp_t2:Sp_c20_PCSK9a) Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide Targets endogenous mouse locus Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
SaC9-g1 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaC9-g2 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaC9-g3 Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
SaLoxP1-modified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP1-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-modified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-unmodified Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Sa_Ai9_L Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016) Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Sa_Ai9_R Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016) Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
SapI-GG stuffer (CasΦ-1) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-1 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-2) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-2 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-3) Guide - [In Vitro] [Genome Editors] [Human] Matched Fields: category : Guide Non-targeting guide RNA targeting compatible with CasΦ-3 Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
SpyCas9 g-loxP2_C9 Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This sgRNA targets the mTmG transgene Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
TLR7-g2-REV Guide - [In Vitro] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide Show Experiments (2) Validating Traffic Light Reporter 7 (TLR7) Mouse Model for NHEJ in Heterozygous Blastocysts Validating Traffic Light Reporter 7 (TLR7) Mouse Model for HDR in Heterozygous Blastocysts
TRAC_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_03 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_04 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_05 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_01 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_02 Guide - [In Vitro] [Biological Systems] [Human] Matched Fields: category : Guide Targets endogenous human locus Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
g-11_C9 Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide sgRNA targeting CFTR exon 11 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-38330_C12a Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide gRNA targeting HPRT locus Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-45_C12a Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched Fields: category : Guide gRNA targeting CFTR inton-22-23 Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-loxP2_C9 Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
g-loxPbot_C12a Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at two sites Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
gRNA #8 Guide - [In Vivo, In Vitro] [Collaborative Opportunity Fund] [Rhesus macaque] Matched Fields: category : Guide Show Experiments (2) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
sg298 Guide - [In Vivo, In Vitro] [Collaborative Opportunity Fund, Delivery Systems Initiative] [Human, Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Show Experiments (3) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Podocyte-specific gene editing in human kidney organoids
sg298 Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes at multiple sites. 2'-O-Methyl at 3 first and last bases, 3' phosphorothioate bonds between first 3 and last 2 bases Show Experiments (2) Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
sgAi9L Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Human, Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells
sgAi9L Guide Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes
sgAi9R Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Human, Mouse] Matched Fields: category : Guide This sgRNA targets the Ai9 and related transgenes Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells

246 results in Guides

Organism	Compatibility	Name	Description	Source	View Associated..
Human	AsCas12a>	3849 45-5'	Targets endogenous human locus	IDT	Show Experiments (1) Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Human	SpyCas9>	3849 C>T loci		IDT	Show Experiments (1) Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Human	SpyCas9>	AAVS1_site_01	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_02	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_03	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_04	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_05	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_06	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_07	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_08	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_09	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_10	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_11	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_12	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_13	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	AAVS1_site_14	Targets AAVS1 safe harbor locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 1 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 10 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 11 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 2 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 3 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 4 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 5 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 6 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 7 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 8 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	LbCas12a>	ABE8e-Cas12a Guide 9 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas12a
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 1 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 10 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 2 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 3 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 4 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 5 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 6 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 7 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 8 CCR5 Rhesus		David Liu lab's plasmid clone	Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Rhesus macaque	SpyCas9>	ABE8e-Cas9 Guide 9 CCR5 Rhesus			Show Experiments (1) Rhesus macaque CCR5 gRNA screening using ABE8e-Cas9
Mouse	SpyCas9>	Ai14 gRNA	This sgRNA targets the Ai9 and related transgenes at multiple sites	IDT	Show Experiments (2) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain
Mouse	SauCas9>	Ai9 SaCas9 Guide A	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Mouse	SauCas9>	Ai9 SaCas9 Guide B	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Human	SpyCas9>	B2M		IDT	Show Experiments (1) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting B2M locus
Human	SpyCas9>	B2M_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	B2M_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SauCas9>	BCM_ssAAV5-Sa_sgB	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Mouse	SpyCas9>	BCM_ssAAV5-Sp_sgA	This sgRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Mouse	SpyCas9>	BCM_ssAAV5-Sp_sgB	This sgRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Independent validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Human	SpyCas9>	CBLB_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CBLB_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CBLB_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CBLB_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CBLB_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_11	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_13	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_14	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_15	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CCR5_site_16	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_10	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_11	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_12	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CTLA4_site_13	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_10	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	CXCR4_site_11	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	CasΦ-1>	Cas12j-GFP1 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP1 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP10 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP10 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP11 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP12 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP13 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP14 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP14 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP15 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP16 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP17 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP18 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP19 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP2 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP2 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP20 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP21 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP22 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP23 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP3 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP3 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP4 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP4 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-1>	Cas12j-GFP5 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP5 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP5 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP6 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP6 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP7 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP7 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP8 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP8 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	Cas12j-GFP9 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	Cas12j-GFP9 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	SpyCas9>	Cas9-CFTR-R553X	CFTR-R553X	IDT	Show Experiments (1) Inhibitory effect of Cas9 RNP alone on S10- or FSDS315-mediated GFP protein delivery to HeLa cells
Human	SauCas9>	DMD low gRNA-1	One of two low-off target gRNAs delivred by dual gRNA AAV vector pAAV[2gRNA]-mCherry-U6>{SagRNA#1*}:{SagRNA#2}	VectorBuilder	Show Experiments (1) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids.
Human	SauCas9>	DMD low gRNA-2	One of two low-off target gRNAs delivred by dual gRNA AAV vector AAV-gRNA	VectorBuilder	Show Experiments (2) Delivery of saCas9 and gRNAs to nephron epithelia by AAV2 in kidney organoids. Evaluation of DNA damage, cellular toxicity and inflammatory markers following saCas9 and gRNAs delivery by AAV2 in kidney organoids.
Human	SpyCas9>	FAS_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	FAS_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	FAS_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	FAS_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	FAS_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SpyCas9>	GER10-ABE-REV	sgRNA target sequence for A base editor in Venus	IDT	Show Experiments (1) Validating Gene Editing Reporter 10 (GER10) Mouse Model in Heterozygous Blastocysts
Mouse	SpyCas9>	GER12-g1-FWD		IDT	Show Experiments (1) Validating Gene Editing Reporter 12 (GER12) Mouse Model in Heterozygous Blastocysts
Mouse	SpyCas9>	GER12-g2-FWD		IDT	Show Experiments (1) Validating Gene Editing Reporter 12 (GER12) Mouse Model in Heterozygous Blastocysts
Mouse	AsCas12a>	GER14-g1-Cpf1-FWD		IDT	Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
Mouse	SauCas9>	GER14-g1-SaC9-FWD		lab IVT	Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
Mouse	SpyCas9>	GER14-g1-SpC9-FWD		IDT	Show Experiments (1) Validating Gene Editing Reporter 14 (GER14) Mouse Model in Heterozygous Blastocysts
Mouse	SpyCas9>	GER18/19 gRNA2 FWD	5' guide flanking IVS2-654 C>T mutation	IDT	Show Experiments (2) Validating Gene Editing Reporter 18 (GER18) Mouse Model in Heterozygous Blastocysts Validating Gene Editing Reporter 19 (GER19) Mouse Model in Heterozygous Blastocysts
Mouse	SpyCas9>	GER18/19 gRNA3 FWD	3' guide flanking IVS2-654 C>T mutation	IDT	Show Experiments (2) Validating Gene Editing Reporter 18 (GER18) Mouse Model in Heterozygous Blastocysts Validating Gene Editing Reporter 19 (GER19) Mouse Model in Heterozygous Blastocysts
Mouse	SauCas9>	L1-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (3) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Mouse	SauCas9>	L1-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	L2-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (2) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Independent validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Mouse	SauCas9>	L2-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	L3-modifed	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	L3-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Human	SpyCas9>	LAG3_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	LAG3_site_10	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	McCray_CFTR_Cas9_Guide1	Targets endogenous human locus	IDT	Show Experiments (1) Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
Human	AsCas12a>	NKG2A	gRNA targeting human NKG2A exon 3	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas12a in NK cells.
Human	SpyCas9>	Negative control gRNA	Negative control guide RNA avoid any targets in human/mouse/rat	IDT	Show Experiments (2) Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system
Human	SpyCas9>	Negative control gRNA	Negative control guide RNA avoid any targets in human/mouse/rat	IDT	Show Experiments (1) Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system
Human	SpyCas9>	PDCD1_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_10	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_11	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_12	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_13	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_14	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_15	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PDCD1_site_16	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN2_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN2_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN2_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_06	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_07	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_08	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	PTPN6_site_09	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Mouse	SpyCas9>	Pcsk9 Exon 1 splice domain	Pcsk9 Exon 1 splice domain	Synthego	Show Experiments (2) Pcsk9 adenine base editor efficiency in liver and nonliver tissue Independent validation of Chaikof delivery platform using virus-like particle (VLP) delivery to the mouse liver
Mouse	SauCas9>	R1-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	R1-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	R2-modified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (2) Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	R2-unmodified	This gRNA targets the Ai9 and related transgenes	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SpyCas9>	R26-1		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
Mouse	SpyCas9>	R26-2		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
Mouse	SpyCas9>	R26-3		IDT	Show Experiments (2) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9 Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Homozygous Blastocysts using SpCas9
Mouse	SpyCas9>	R26-52		IDT	Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
Mouse	SpyCas9>	R26-59		IDT	Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
Mouse	SpyCas9>	R26-69		IDT	Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SpCas9
Mouse	SpyCas9>	STS118 (TLR-MCV1a; Sp_t2-PS:Sp_c20_TLR_MCV1a)	Targets traffic light reporter transgene, CY3 labeled	in house production	Show Experiments (1) Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain
Human	SpyCas9>	STS118 (TLR-MCV1a; Sp_t2:Sp_c20_TLR_MCV1a)	Targets traffic light reporter transgene	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
Human	SpyCas9>	STS119 (TLR-MCV1b; Sp_t2:Sp_c20_TLR_MCV1b)	Targets traffic light reporter transgene	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
Human	SpyCas9>	STS120 (TLR1; Sp_t2:Sp_c20_TLR1)	Targets traffic light reporter transgene	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA to activate the TLR1 reporter in human cells
Mouse	SpyCas9>	STS134 (PCSK9b; Sp_t2:Sp_c20_PCSK9b)	Targets endogenous mouse locus	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SpyCas9>	STS135 (PCSK9c; Sp_t2:Sp_c20_PCSK9c)	Targets endogenous mouse locus	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SpyCas9>	STS159 (mTmG; Sp_t2-PS:Sp_c0_mTmG)	This sgRNA targets the mTmG transgene	in house production	Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Mouse	SpyCas9>	STS159 (mTmG; Sp_t2-PS:Sp_c20_mTmG)	This sgRNA targets the mTmG transgene	in house production	Show Experiments (1) Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
Mouse	SpyCas9>	STS159 (mTmG; Sp_t2:Sp_c0_mTmG)	This sgRNA targets the mTmG transgene	in house production	Show Experiments (1) Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
Mouse	SpyCas9>	STS159 (mTmG; Sp_t2:Sp_c20_mTmG)	This sgRNA targets the mTmG transgene	in house production	Show Experiments (3) Testing newly chemically modified crRNA and tracrRNA in mTmG mouse embryonic fibroblasts Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center
Mouse	SpyCas9>	STS204 (DNMT1; Sp_t2:Sp_c20_Dnmt1)	For endogenous locus	in house production	Show Experiments (1) Testing preparation for independent validation at The Jackson Laboratory Small Animal Testing Center
Mouse	SpyCas9>	STS204 (DNMT1; Sp_t41:Sp_c20_Dnmt1)	Targets endogenous mouse locus	in house production	Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
Mouse	SpyCas9>	STS205 (BACE1; Sp_t41:Sp_c20_Bace1)	Targets endogenous mouse locus	in house production	Show Experiments (2) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
Mouse	SpyCas9>	STS96 (PCSK9a; Sp_t2:Sp_c20_PCSK9a)	Targets endogenous mouse locus	in house production	Show Experiments (1) Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
Mouse	SauCas9>	SaC9-g1			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9>	SaC9-g2			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9>	SaC9-g3			Show Experiments (1) Validating Traffic Light Reporter 2 (TLR2) Mouse Model in Heterozygous Blastocysts using SaCas9
Mouse	SauCas9>	SaLoxP1-modified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	SaLoxP1-unmodified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	SaLoxP2-modified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	SaLoxP2-unmodified	This gRNA targets the mTmG, Ai9 and related transgenes at two sites	Vector encoded	Show Experiments (1) Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Mouse	SauCas9>	Sa_Ai9_L	This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016)		Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Mouse	SauCas9>	Sa_Ai9_R	This gRNA targets the Ai9 and related transgenes, has modified scaffold (Tabebordbar Science 2016)		Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Human	CasΦ-1>	SapI-GG stuffer (CasΦ-1)	Non-targeting guide RNA targeting compatible with CasΦ-1		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-2>	SapI-GG stuffer (CasΦ-2)	Non-targeting guide RNA targeting compatible with CasΦ-2		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Human	CasΦ-3>	SapI-GG stuffer (CasΦ-3)	Non-targeting guide RNA targeting compatible with CasΦ-3		Show Experiments (1) Testing newly discovered Biggie Phage editors in human cells
Mouse	SpyCas9>	SpyCas9 g-loxP2_C9	This sgRNA targets the mTmG transgene	IDT	Show Experiments (1) Independent validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Mouse	SpyCas9>	TLR7-g2-REV		IDT	Show Experiments (2) Validating Traffic Light Reporter 7 (TLR7) Mouse Model for NHEJ in Heterozygous Blastocysts Validating Traffic Light Reporter 7 (TLR7) Mouse Model for HDR in Heterozygous Blastocysts
Human	SpyCas9>	TRAC_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRAC_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRAC_site_03	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRAC_site_04	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRAC_site_05	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRBC1_site_01	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	TRBC1_site_02	Targets endogenous human locus	lab IVT	Show Experiments (1) A novel human T cell platform to define biological adverse effects of genome editing
Human	SpyCas9>	g-11_C9	sgRNA targeting CFTR exon 11	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Human	AsCas12a>	g-38330_C12a	gRNA targeting HPRT locus	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Human	AsCas12a>	g-45_C12a	gRNA targeting CFTR inton-22-23	IDT	Show Experiments (1) Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
Mouse	SpyCas9>	g-loxP2_C9	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
Mouse	AsCas12a>	g-loxPbot_C12a	This sgRNA targets the Ai9 and related transgenes at two sites	IDT	Show Experiments (1) Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
Rhesus macaque	SpyCas9>	gRNA #8		IDT	Show Experiments (2) Delivery of ABE8e-Cas9 RNP using Shuttle peptide candidates to rhesus monkey airway epithelial cells cultured at the air liquid interface targeting CCR5 locus. Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
Human Mouse	SpyCas9>	sg298	This sgRNA targets the Ai9 and related transgenes at multiple sites	Synthego	Show Experiments (3) Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea Podocyte-specific gene editing in human kidney organoids
Mouse	SpyCas9>	sg298	This sgRNA targets the Ai9 and related transgenes at multiple sites. 2'-O-Methyl at 3 first and last bases, 3' phosphorothioate bonds between first 3 and last 2 bases	Synthego	Show Experiments (2) Independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Repeat experiment of independent validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
Human Mouse	SpyCas9>	sgAi9L	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells
		sgAi9L	This sgRNA targets the Ai9 and related transgenes
Human Mouse	SpyCas9>	sgAi9R	This sgRNA targets the Ai9 and related transgenes	IDT	Show Experiments (3) Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells

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