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3849 45-5' - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
AAVS1_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_10 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_11 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_12 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_13 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
AAVS1_site_14 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets AAVS1 safe harbor locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
Ai14 gRNA - Guide - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Experiments Second site validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
Ai9 SaCas9 Guide A - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Ai9 SaCas9 Guide B - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
B2M_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
B2M_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
BCM_ssAAV5-Sa_sgB - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgA - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
BCM_ssAAV5-Sp_sgB - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
CBLB_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CBLB_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_11 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_13 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_14 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_15 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CCR5_site_16 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_10 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_11 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_12 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CTLA4_site_13 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_10 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
CXCR4_site_11 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
Cas12j-GFP1 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP1 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP10 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP11 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP12 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP13 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP14 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP15 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP16 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP17 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP18 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP19 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP2 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP20 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP21 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP22 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP23 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP3 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP4 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP5 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP6 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP7 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP8 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
Cas12j-GFP9 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Guide targeting eGFP compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
FAS_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
FAS_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
L1-modified - Guide - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Second site validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L1-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L2-modified - Guide - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Second site validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
L2-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-modifed - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
L3-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
LAG3_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
LAG3_site_10 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
McCray_CFTR_Cas9_Guide1 - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells
NKG2A - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide gRNA targeting human NKG2A exon 3 Experiments Gene editing in vitro by various peptide variants delivering Cas12a in NK cells.
PDCD1_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_10 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_11 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_12 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_13 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_14 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_15 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PDCD1_site_16 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN2_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_06 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_07 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_08 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
PTPN6_site_09 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
R1-modified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R1-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-modified - Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
R2-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the Ai9 and related transgenes Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
STS118 (TLR-MCV1a; Sp_t2-PS:Sp_c20_TLR_MCV1a) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets traffic light reporter transgene, CY3 labeled Experiments Delivery of RNP containing chemically modified crRNA C20 with chemically modified tracrRNA T2-PS to determine the RNP distribution in TLR-MCV mouse brain
STS118 (TLR-MCV1a; Sp_t2:Sp_c20_TLR_MCV1a) - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide Targets traffic light reporter transgene Experiments Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS119 (TLR-MCV1b; Sp_t2:Sp_c20_TLR_MCV1b) - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide Targets traffic light reporter transgene Experiments Testing newly chemically modified crRNA and tracrRNA to activate the TLR reporter in human cells
STS120 (TLR1; Sp_t2:Sp_c20_TLR1) - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide Targets traffic light reporter transgene Experiments Testing newly chemically modified crRNA and tracrRNA to activate the TLR1 reporter in human cells
STS134 (PCSK9b; Sp_t2:Sp_c20_PCSK9b) - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets endogenous mouse locus Experiments Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS135 (PCSK9c; Sp_t2:Sp_c20_PCSK9c) - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets endogenous mouse locus Experiments Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
STS159 (mTmG; Sp_t2-PS:Sp_c0_mTmG) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets mTmG and related reporter transgenes Experiments Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2-PS:Sp_c20_mTmG) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets mTmG and related reporter transgenes Experiments Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, extended PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c0_mTmG) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets mTmG and related reporter transgenes Experiments Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
STS159 (mTmG; Sp_t2:Sp_c20_mTmG) - Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets mTmG and related reporter transgenes Experiments Testing newly chemically modified crRNA and tracrRNA in mTmG mouse embryonic fibroblasts Testing preparation for validation at The Jackson Laboratory Small Animal Testing Center
STS159 (mTmG; Sp_t2:Sp_c20_mTmG) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets mTmG and related reporter transgenes Experiments Delivery of chemically modified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA to activate the mTmG reporter in mouse brain
STS204 (DNMT1; Sp_t2:Sp_c20_Dnmt1) - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide For endogenous locus Experiments Testing preparation for validation at The Jackson Laboratory Small Animal Testing Center
STS204 (DNMT1; Sp_t41:Sp_c20_Dnmt1) - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets endogenous mouse locus Experiments Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS205 (BACE1; Sp_t41:Sp_c20_Bace1) - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets endogenous mouse locus Experiments Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells Testing newly chemically modified crRNA and tracrRNA in mouse Neuro 2A cells
STS96 (PCSK9a; Sp_t2:Sp_c20_PCSK9a) - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide Targets endogenous mouse locus Experiments Testing newly chemically modified crRNA and tracrRNA in mouse Hepa 1-6 cells
SaLoxP1-modified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP1-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-modified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SaLoxP2-unmodified - Guide - [In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This gRNA targets the mTmG, Ai9 and related transgenes at two sites Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
SapI-GG stuffer (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Non-targeting guide RNA targeting compatible with CasΦ-1 Experiments Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Non-targeting guide RNA targeting compatible with CasΦ-2 Experiments Testing newly discovered Biggie Phage editors in human cells
SapI-GG stuffer (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human] Matched on: category --> Guide Non-targeting guide RNA targeting compatible with CasΦ-3 Experiments Testing newly discovered Biggie Phage editors in human cells
SpyCas9 g-loxP2_C9 - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This sgRNA targets the mTmG transgene Experiments Validation for McCray Delivery Team: Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
TRAC_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_03 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_04 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRAC_site_05 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_01 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
TRBC1_site_02 - Guide - [In Vitro] [Biological Systems] [Human] Matched on: category --> Guide Targets endogenous human locus Experiments A novel human T cell platform to define biological adverse effects of genome editing
g-11_C9 - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide sgRNA targeting CFTR exon 11 Experiments Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-38330_C12a - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide gRNA targeting HPRT locus Experiments Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-45_C12a - Guide - [In Vitro] [Delivery Systems Initiative] [Human] Matched on: category --> Guide gRNA targeting CFTR inton-22-23 Experiments Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.
g-loxP2_C9 - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes Experiments Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
g-loxPbot_C12a - Guide - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes at two sites Experiments Shuttle peptides enable in vivo gene editing with Cas9 and Cas12a RNP in mouse airway epithelia
sg298 - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes at multiple sites. 2'-O-Methyl at 3 first and last bases, 3' phosphorothioate bonds between first 3 and last 2 bases Experiments Repeat experiment of second site validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear Second site validation of Chen delivery platform using LNPs to deliver CRISPR/Cas9 to mouse inner ear
sg298 - Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes at multiple sites Experiments Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in primary fibroblast cells from adult Ai14 mouse cochlea Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea
sgAi9L - Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Human, Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes Experiments Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells
sgAi9L - Guide Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes
sgAi9R - Guide - [In Vivo, In Vitro] [Delivery Systems Initiative] [Human, Mouse] Matched on: category --> Guide This sgRNA targets the Ai9 and related transgenes Experiments Testing AAV5 for activation of tdTomato in HEK293T cells Testing AAV5 for activation of tdTomato in mouse airway Testing AAV5 for activation of tdTomato in mouse airway club and ciliated cells

197 results in Guides

Category	Name	Description	View Associated..
Guide	3849 45-5'	Targets endogenous human locus	Experiments Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells
Guide	AAVS1_site_01	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_02	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_03	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_04	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_05	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_06	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_07	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_08	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_09	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_10	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_11	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_12	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_13	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	AAVS1_site_14	Targets AAVS1 safe harbor locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	Ai14 gRNA	This sgRNA targets the Ai9 and related transgenes at multiple sites	Experiments Second site validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
Guide	Ai9 SaCas9 Guide A	This gRNA targets the Ai9 and related transgenes	Experiments Validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Guide	Ai9 SaCas9 Guide B	This gRNA targets the Ai9 and related transgenes	Experiments Validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Guide	B2M_site_01	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_02	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_03	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_06	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	B2M_site_07	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	BCM_ssAAV5-Sa_sgB	This gRNA targets the Ai9 and related transgenes	Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Guide	BCM_ssAAV5-Sp_sgA	This sgRNA targets the Ai9 and related transgenes	Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Guide	BCM_ssAAV5-Sp_sgB	This sgRNA targets the Ai9 and related transgenes	Experiments Validation for Gao Delivery Team: Testing ssAAV5 delivered intratracheally for editing activity in lung epithelia in Ai9 mice
Guide	CBLB_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CBLB_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CBLB_site_06	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CBLB_site_08	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CBLB_site_09	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_03	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_07	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_08	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_09	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_11	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_13	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_14	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_15	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CCR5_site_16	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_01	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_02	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_03	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_06	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_07	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_08	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_09	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_10	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_11	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_12	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CTLA4_site_13	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_01	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_02	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_03	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_06	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_07	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_08	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_10	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	CXCR4_site_11	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	Cas12j-GFP1 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP1 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP10 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP10 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP11 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP12 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP13 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP14 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP14 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP15 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP16 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP17 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP18 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP19 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP2 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP2 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP20 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP21 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP22 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP23 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP3 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP3 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP4 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP4 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP5 (CasΦ-1)	Guide targeting eGFP compatible with CasΦ-1	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP5 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP5 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP6 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP6 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP7 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP7 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP8 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP8 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP9 (CasΦ-2)	Guide targeting eGFP compatible with CasΦ-2	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	Cas12j-GFP9 (CasΦ-3)	Guide targeting eGFP compatible with CasΦ-3	Experiments Testing newly discovered Biggie Phage editors in human cells
Guide	FAS_site_01	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	FAS_site_02	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	FAS_site_03	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	FAS_site_04	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	FAS_site_05	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	L1-modified	This gRNA targets the Ai9 and related transgenes	Experiments Testing gRNA sequence and gRNA scaffold modified in Ai9 mice. Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Second site validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Guide	L1-unmodified	This gRNA targets the Ai9 and related transgenes	Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Guide	L2-modified	This gRNA targets the Ai9 and related transgenes	Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro Second site validation of Deverman delivery platform using engineered AAVs to deliver CRSIPR/Cas9 to mouse brain
Guide	L2-unmodified	This gRNA targets the Ai9 and related transgenes	Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Guide	L3-modifed	This gRNA targets the Ai9 and related transgenes	Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Guide	L3-unmodified	This gRNA targets the Ai9 and related transgenes	Experiments Selection of gRNA sequences and gRNA scaffold modification lead to improved editing of the Ai9 locus in vitro
Guide	LAG3_site_01	Targets endogenous human locus	Experiments A novel human T cell platform to define biological adverse effects of genome editing
Guide	LAG

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197 results in Guides

3849 45-5' - Guide - [In Vitro] [Delivery Systems Initiative] [Human]

AAVS1_site_01 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_02 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_03 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_06 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_07 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_08 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_09 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_10 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_11 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_12 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_13 - Guide - [In Vitro] [Biological Systems] [Human]

AAVS1_site_14 - Guide - [In Vitro] [Biological Systems] [Human]

Ai14 gRNA - Guide - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse]

Ai9 SaCas9 Guide A - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse]

Ai9 SaCas9 Guide B - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse]

B2M_site_01 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_02 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_03 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_06 - Guide - [In Vitro] [Biological Systems] [Human]

B2M_site_07 - Guide - [In Vitro] [Biological Systems] [Human]

BCM_ssAAV5-Sa_sgB - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse]

BCM_ssAAV5-Sp_sgA - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse]

BCM_ssAAV5-Sp_sgB - Guide - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse]

CBLB_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

CBLB_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

CBLB_site_06 - Guide - [In Vitro] [Biological Systems] [Human]

CBLB_site_08 - Guide - [In Vitro] [Biological Systems] [Human]

CBLB_site_09 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_03 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_07 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_08 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_09 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_11 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_13 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_14 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_15 - Guide - [In Vitro] [Biological Systems] [Human]

CCR5_site_16 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_01 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_02 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_03 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_06 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_07 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_08 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_09 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_10 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_11 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_12 - Guide - [In Vitro] [Biological Systems] [Human]

CTLA4_site_13 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_01 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_02 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_03 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_04 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_05 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_06 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_07 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_08 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_10 - Guide - [In Vitro] [Biological Systems] [Human]

CXCR4_site_11 - Guide - [In Vitro] [Biological Systems] [Human]

Cas12j-GFP1 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP1 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP10 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP10 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP11 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP12 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP13 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP14 (CasΦ-2) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP14 (CasΦ-3) - Guide - [In Vitro] [Genome Editors] [Human]

Cas12j-GFP15 (CasΦ-1) - Guide - [In Vitro] [Genome Editors] [Human]