29 results in Genome Editors

ABE8e

Genome Editor  - [In Vitro] [Delivery Systems, Genome Editors, Collaborative Opportunity Fund] [Mouse, Rhesus macaque]
Matched Fields: category : Genome Editor
Tad8e deaminase fused to a nickase (D10A) spCas9

ABE8e

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
Catalytically impaired Cas fused to TadA deaminase

SaCas9

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor

SaCas9 (AAV-SaCas9)

Genome Editor  - [In Vitro] [Biological Effects] [Human]
Matched Fields: category : Genome Editor
SaCas9 delivered by AAV-SaCas9 vector

AsCas12a (IDT and Feldan Therapeutics)

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor

CasΦ-2

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

CasΦ-3

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

SauCas9

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor

SpyCas9-3xNLS

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal
Show Experiments (5)

TadA-8e V106W

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Catalytically impaired Cas fused to evolved TadA deaminase (TadA-8e V106W)

ABE8e-Cas12a

Genome Editor  - [In Vitro] [Delivery Systems, Genome Editors, Collaborative Opportunity Fund] [Rhesus macaque]
Matched Fields: category : Genome Editor
A-to-G base editor

Alt-R® S.p. Cas9 Nuclease V3

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
Recombinant S. pyogenes Cas9 nuclease, purified from an E. coli strain expressing the nuclease. Contains nuclear localization sequence (NLS) and C-terminal 6-His tag. Provided in solution at 10 µg/µL. 100 µg of Cas9 nuclease = 610 pmol.

CasΦ-1

Genome Editor  - [In Vitro] [Genome Editors] [Human]
Matched Fields: category : Genome Editor
Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies

CleanCap® Cas9 mRNA (5moU)

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

GFP-NLS

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Nuclear targeted GFP

sNLS-SpCas9-sNLS

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Collaborative Opportunity Fund, Biological Effects, Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 with N- and C-terminal SV40 NLS

CleanCap® Cas9

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

CleanCap® Fluc

Genome Editor  - [In Vivo] [Delivery Systems] [Mouse]
Matched Fields: category : Genome Editor
Firefly luciferase mRNA capped using CleanCap. It is polyadenylated, modified with 5-methoxyuridine and optimized for mammalian systems. It mimics a fully processed mature mRNA.

Cre recombinase

Genome Editor  - [In Vitro] [Delivery Systems] [Human]
Matched Fields: category : Genome Editor
Cre recombinase delivered by plasmid (see vector details)

SaCas9

Genome Editor  - [In Vivo] [Animal Reporter and Testing Center] [Mouse]
Matched Fields: category : Genome Editor

SpyCas9-3xNLS

Genome Editor  - [In Vivo, In Vitro] [Delivery Systems, Animal Reporter and Testing Center] [Human, Mouse]
Matched Fields: category : Genome Editor
SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal

29 results in Genome Editors

Type Subtype Name Description Source View Associated...
Base Editor (SpCas9) Adenine base editor ABE8e Tad8e deaminase fused to a nickase (D10A) spCas9 David Liu Lab
Base Editor (SpCas9) Adenine base editor ABE8e Catalytically impaired Cas fused to TadA deaminase Liu Lab
Base Editor (SpCas9) Adenine base editor ABE8e-Cas9 A-to-G base editor Feldan Therapeutics
Cas Nuclease AsCas12a (Cpf1) AsCas12a (Feldan Therapeutics) Feldan Therapeutics
Recombinase Cre recombinase Cre recombinase Cre recombinase delivered by AAV (see vector details)
Cas Nuclease Cas9 SaCas9 Leong Lab
Cas Nuclease Cas9 SaCas9 (AAV-SaCas9) SaCas9 delivered by AAV-SaCas9 vector VectorBuilder
Cas Nuclease AsCas12a (Cpf1) AsCas12a (IDT and Feldan Therapeutics) IDT and Feldan Therapeutics
Cas Nuclease Cas12j CasΦ-2 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Cas Nuclease Cas12j CasΦ-3 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Cas Nuclease Cas9 SaCas9-Lagor William Lagor, Baylor College Of Medicine
Cas Nuclease Cas9 SauCas9
Cas Nuclease Cas9 SpCas9 IDT
Cas Nuclease Cas9 SpCas9 HA-SV40NLS-SpCas9-SV40NLS Vector Encoded
Cas Nuclease Cas9 SpCas9 (Feldan Therapeutics) Feldan Therapeutics
Cas Nuclease Cas9 SpyCas9-3xNLS SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal Sontheimer lab
Show Experiments (5)
Base Editor (SpCas9) Adenine base editor TadA-8e V106W Catalytically impaired Cas fused to evolved TadA deaminase (TadA-8e V106W) Chaikof Lab
Base Editor (Cas12a) Adenine base editor ABE8e-Cas12a A-to-G base editor Liu lab
Cas Nuclease Cas9 Alt-R® S.p. Cas9 Nuclease V3 Recombinant S. pyogenes Cas9 nuclease, purified from an E. coli strain expressing the nuclease. Contains nuclear localization sequence (NLS) and C-terminal 6-His tag. Provided in solution at 10 µg/µL. 100 µg of Cas9 nuclease = 610 pmol. Integrated DNA Technologies
Cas Nuclease Cas12j CasΦ-1 Compact editor of the Cas12j family identified in biggie phage from metagenomic assemblies Jennifer Doudna Lab
Cas Nuclease Cas9 CleanCap® Cas9 mRNA (5moU) SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Reporter Fluorescent protein GFP-NLS Nuclear targeted GFP Expressed From (Escherichia coli BL21DE3)
Cas Nuclease Cas9 SaCas9
Cas Nuclease Cas9 sNLS-SpCas9-sNLS SpCas9 with N- and C-terminal SV40 NLS Aldevron 9212-5MG
Cas Nuclease Cas9 CleanCap® Cas9 SpCas9 mRNA with 2 NLS signals, HA tag and capped using CleanCap. It is polyadenylated, substituted with a modified uridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Reporter Bioluminescent CleanCap® Fluc Firefly luciferase mRNA capped using CleanCap. It is polyadenylated, modified with 5-methoxyuridine and optimized for mammalian systems. It mimics a fully processed mature mRNA. Trilink Biotechnologies
Recombinase Cre recombinase Cre recombinase Cre recombinase delivered by plasmid (see vector details)
Cas Nuclease Cas9 SaCas9 Vector Encoded (ssaav5-sga+sgb-u1a.gfp)
Cas Nuclease Cas9 SpyCas9-3xNLS SpyCas9-3xNLS is type II-A Cas9 from Streptococcus pyogenes strain SF370. It was expressed from pMCSG7 bacterial expressing vector and purified from Escherichia coli Rosetta DE3 strain. SpyCas9 fused to 3 NLS: C-Myc-like NLS at the N-terminal SV40 NLS and Nucleoplasmin NLS at the C-terminal Sontheimer lab