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Somatic Cell Genome Editing Consortium | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
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Enabling Nanoplatforms for Targeted In Vivo Delivery of CRISPR/Cas9 Riboncleoproteins in the Brain
Poly(Amine-Co-Ester)s for Targeted Delivery In Vivo of Gene Editing Agents to Bone Marrow and Lung
Expanding CRISPR-Cas Editing Technology through Exploration of Novel Cas Proteins and DNA Repair Systems
Human Microtissues for In Situ Detection and Functional Measurement of Adverse Consequences Caused by Genome Editing
Efficient In Vivo RNP-Based Gene Editing in the Sensory Organ Inner Ear Using Bioreducible Lipid Nanoparticles
A Novel Human T-Cell Platform to Define Biological Effects of Genome Editing
The Jackson Laboratory Gene Editing Testing Center - Ghiran Validation (Ghiran, Ionita)
Evolving High Potency AAV Vectors for Neuromuscular Genome Editing - submission 3
Enhancing CRISPR Gene Editing in Somatic Tissues by Chemical Modification of Guides and Donors
Developing methods for unbiased off-target genome editing analysis in vivo
Single Cell Profiling to Define Biomarkers of Photoreceptor Dysfunction After Genome Editing Within PSC-Derived Organoids
Enabling Nanoplatforms for Targeted In Vivo Delivery of CRISPR/Cas9 Riboncleoproteins in the Brain
Endothelial-targeted Adenovirus for Organ-selective Gene Editing In Vivo
Multicell Type Human Liver on Chip Microphysiological Platform to Examine CRISPR-Based Gene Modulation
Highly Specific ZFN-Based HSC Gene Editing Therapies Identified By In Vivo Barcode Nanoparticle Screens And Rationally Designed mRNA - submission 2
Expanding the Scope of Base Editing
Efficient In Vivo RNP-Based Gene Editing in the Sensory Organ Inner Ear Using Bioreducible Lipid Nanoparticles
Endothelial-targeted Adenovirus for Organ-selective Gene Editing In Vivo
Evolving High Potency AAV Vectors for Neuromuscular Genome Editing
Enhancing CRISPR Gene Editing in Somatic Tissues by Chemical Modification of Guides and Donors
Evolving High Potency AAV Vectors for Neuromuscular Genome Editing
Building the Mitochondrial Genome Editing Repertoire
Non-Invasive Monitoring of CRISPR/Cas-Edited Chimeric Antigen Receptor T (CAR-T) Cells with Reporter Gene-Based Magnetic Resonance Imaging and Positron Emission Tomography
Base Editing in Rhesus Airway Epithelial
PNA Nanoparticles for Gene Editing In Vivo
Cell-specific Nanocarrier with Endocytic and Endosomolytic Activities for Therapeutic Genome Editing
Novel Grafted Terpolymers for Targeted Delivery of CRISPR/Cas9-mediated Precise Genome Editing to the Brain
Rhesus Macaque Somatic Cell Gene Editing Resource-U24
Development of a nanoparticle-based gene editing technology for neurological applications
Guide Engineering to Enhance the Safety and Efficacy of Base Editing in vivo
The Jackson Laboratory Gene Editing Testing Center - Zhou Validation (Zhou, Jiangbing)
Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides
Molecular MRI for in vivo tracking of gene editing and gene edited cells
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Deverman Validation (Deverman, Benjamin)
Expanding CRISPR-Cas Editing Technology through Exploration of Novel Cas Proteins and DNA Repair Systems
Develop Combinatorial Non-Viral and Viral CRISPR Delivery for Lung Diseases
Develop Combinatorial Non-Viral and Viral CRISPR Delivery for Lung Diseases
Delivery Technologies for In Vivo Genome Editing
Focused Ultrasound-mediated Delivery of Gene-editing Elements to the Brain for Neurodegenerative Disorders
Development of a single AAV vector CRISPR-CasΦ platform technology
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC)
Non-Invasive Tracking of Genome-Corrected iPS cells in ALS - Submission 2
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Gao Validation (Gao, Guang-Ping )
Non-Invasive Tracking of Genome-Corrected iPS cells in ALS
Improving the Safety of Genome Editing With Human Kidney Organoids
Bioengineered Red Blood Cells as Extracellular Vesicle-Mediated Delivery Platforms for Gene Editing Machinery
Novel AAVs Engineered for Efficient and Noninvasive Cross-Species Gene Editing Throughout the Central Nervous System
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - SATC-Sontheimer, Submission 2 (On- and Off-target data))
The Jackson Laboratory Gene Editing Testing Center - Saltzman Validation (Saltzman, Mark)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Asokan Validation (Asokan, Aravind)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - McCray Validation (McCray Jr., Paul)
The Jackson Laboratory Gene Editing Testing Center - Chen Validation (Chen, Zheng-Yi)
The Jackson Laboratory Gene Editing Testing Center - Gong Validation (Gong, Shaoqin)
Enabling Nanoplatforms for Targeted In Vivo Delivery of CRISPR/Cas9 Riboncleoproteins in the Brain - submission 3
Enabling Nanoplatforms for Targeted In Vivo Delivery of CRISPR/Cas9 Riboncleoproteins in the Brain - submission 4
Develop Combinatorial Non-Viral and Viral CRISPR Delivery for Lung Diseases - submission 3
Efficient In Vivo RNP-Based Gene Editing in the Sensory Organ Inner Ear Using Bioreducible Lipid Nanoparticles - submission 3
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Dahlman Validation (Dahlman, James)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Curiel Validation (Curiel, David Terry)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Lam Validation (Lam, Kit S)
Highly Specific ZFN-Based HSC Gene Editing Therapies Identified By In Vivo Barcode Nanoparticle Screens And Rationally Designed mRNA
Identification and optimization of shuttle peptides-mediated local RNP delivery of editing complex in the sensory organs of the inner ear and retina in vivo in mice and the pig
The Jackson Laboratory Gene Editing Testing Center - Bankiewicz Validation (Bankiewicz, Krystof)
Cas9 ribonucleoprotein delivery targeted to kidney epithelium
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - SATC-Zhou, Submission 2 (Off-target data)
Development of a nanoparticle-based gene editing technology for neurological applications - submission 2
Cas9 ribonucleoprotein delivery targeted to kidney epithelium
NHP AAV Tropism
Novel virus-like particles (VLPs) for precise delivery of base-editors in iPSC disease models
Nanoparticle-based Delivery of Mitochondrial Base Editors
*DEMO STUDY* For Toolkit demonstration purposes only
Multicell Type Human Liver on Chip Microphysiological Platform to Examine CRISPR-Based Gene Modulation - submission 2
SCGE AAV Tropism Supplement: Evaluation Across Multiple Tissues in Mice
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai6HDR_reporter_SauB (Small Animal Reporter Validation) Submission 1
Vascularized kidney organoids on chip for efficacy and toxicity testing of somatic genome editing
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai6HDR_reporter_SpyB (Small Animal Reporter Validation) Submission 1
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai9-SauSpyCas9 (Small Animal Reporter Validation) Submission 1
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai9 (Small Animal Reporter Validation) Submission 1
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Chaikof Validation (Chaikof, Elliot L. )
The Jackson Laboratory Gene Editing Testing Center - Sontheimer Validation (Sontheimer, Eric)
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai9 (Small Animal Reporter Validation) Submission 2
BCM-Rice Resource for the Analysis of Somatic Gene Editing in Mice - Ai9-SauSpyCas9 (Small Animal Reporter Validation) Submission 2
A Novel Human T-Cell Platform to Define Biological Effects of Genome Editing
Knock-in Marmoset Reporters for Non-Invasive Measuring of Genome-Editing Efficiency
The Jackson Laboratory Gene Editing Testing Center - Leong Validation (Leong, Kam)
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - TLR7 small animal reporter, submission 1
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - GER19 small animal reporter, submission 1
Evaluation of LNP-based nanoparticles for systemic delivery of base editors
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - SATC-Gong, Submission 2 (On- and Off-target data)
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - GER10 small animal reporter, submission 1
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - GER12 small animal reporter, submission 1
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - GER14 small animal reporter, submission 1
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - GER18 small animal reporter, submission 1
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - SATC-Chen, Submission 2 (On- and Off-target data)
Comparing the efficiency and cellular impact of non-viral, hepatocyte-targeted delivery vehicles with viral-mediated gene delivery in a microphysiological liver on chip platform
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) - TLR2 small animal reporter, submission 2 (Tier 1 & 2 validation)
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) -SATC-Bankiewicz, Submission 2 (On- and Off-target data)
The Jackson Laboratory Gene Editing Testing Center (JAX-GETC) -SATC-Leong, Submission 2 (On- and Off-target data)
Epigenome Editing Technologies for Treating Diverse Disease
Non-Invasive Tracking of Genome-Corrected iPS cells in ALS - submission 3
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