Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells |
FS48 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000704 |
|
SpCas9 (Feldan Therapeutics) |
FS48 |
Amphiphilic peptide |
McCray_CFTR_Cas9_Guide1 |
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Human |
Primary Airway Epithelia |
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2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
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RNP |
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Measured Values |
Samples Size: | 5 |
|
Mean |
0.97  |
1 |
1.15  |
2 |
0.33  |
3 |
1.2  |
4 |
1.42  |
5 |
0.76  |
| |
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