Primary Airway Epithelia (Human) | SCGE Toolkit

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Summary Projects & Experiments

SCGE ID	13000000023
Name	Primary Airway Epithelia (Human)
Species	Human
Type	Cell
Subtype	Primary cells
Description	Primary airway epithelia from non-CF donors

Source	University of Iowa

Publication Title
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. NCBI

This Model System: Primary Airway Epithelia (Human) is being used ...

Project	Initiative	Contact PI
Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic Peptides Experiments Peptide Shuttle optimization to deliver Cas9 RNP to human airway epithelia cells Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells Gene editing in vitro by various peptide variants delivering Cas RNPs to primary Human airway epithelia cells.	Delivery Systems	Paul B McCray, Jr, MD (University of Iowa)
Base Editing in Rhesus Airway Epithelial Experiments Delivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus	Collaborative Opportunity Fund	Paul B McCray, Jr, MD Alice F Tarantal, PhD David Guay, PhD David R Liu, PhD (University of Iowa)