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ExperimentDelivery of Cas9 RNP using Shuttle peptide candidates to human airway epithelial cells cultured at the air liquid interface targeting CFTR locus
Experiment ConditionFSD115d1
Assay Description: Editing efficiency was assessed using Next Generation Sequencing
Tissue Measured:
Measurement Type:Editing Efficiency
Record ID15000002960

EditorSpCas9 (Feldan Therapeutics)
Delivery SystemFSD115d1
Delivery System SubtypeAmphiphilic peptide
Guide3849 C>T loci
Vector

Model SpeciesHuman
Model NamePrimary Airway Epithelia

Application Method
Application Site
Dosage
Injection Frequency
Injection Rate
Injection Volume
Days post injection
Editor Formatribonucleoprotein (RNP)
Antidote Id
Antidote Description

Measured Values
Samples Size: 6
 
Replicate Result (Editing Efficiency)
Measurement Units: % of reads
Mean 3.55 
1 3.58 
2 3.36 
3 2.61 
4 3.28 
5 4.91 
6 3.58