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ExperimentAAV Tropism project
Experiment ConditionAAV4 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:urinary bladder
Measurement Type:Editing Efficiency
Record ID15000001777

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV4-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 3
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 6.01 
1 5.38 
2 3.66 
4 8.98 
Measurement Units: GC/ug DNA
Mean 8755.33 
1 6191 
2 1955 
3 3759 
4 253 
5 14 
6 40360 
  
AAV4 urinary bladder
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging