Development System AAV Tropism project | SCGE Toolkit Ten AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized for biodistribution across 20 tissues by quantitative PCR and imaging
PI:
William Raymond Lagor, PhD
Jason D Heaney, PhD
Mary E Dickinson, PhD
Guang-Ping Gao, PhD
Stephen A Murray, PhD
Cathleen M Lutz, PhD
Description: Ten AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized for biodistribution across 20 tissues by quantitative PCR and imaging
Delivery Assays:
Genome copies per microgram of total DNA was determined by qPCR
Editing Assay:
Cre activity was assessed by image quantification