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ExperimentAAV Tropism project
Experiment ConditionAAV4 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:eye
Measurement Type:Editing Efficiency
Record ID15000001800

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV4-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 9.22 
1 8.64 
2 9.11 
3 9.4 
4 9.74 
Measurement Units: GC/ug DNA
Mean 27873.4 
1 459 
2 59041 
3
4 18127 
5 61734 
  
AAV4 eye
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging