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ExperimentAAV Tropism project
Experiment ConditionAAV4 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:liver
Measurement Type:Editing Efficiency
Record ID15000001805

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV4-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 9.1 
1 6.8 
2 10.1 
3 10.28 
4 9.21 
Measurement Units: GC/ug DNA
Mean 7150.33 
1
2 4162 
3 34 
4 12959 
5 15626 
6 10119 
  
AAV4 liver
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging