| AAV Tropism project |
| AAV5 females |
| Cre activity was assessed by image quantification |
| heart |
| Editing Efficiency |
| 15000001842 |
|
|
| AAV |
| Viral vector |
|
| AAV5-ZsGreen-Cre; |
|
| Mouse |
| B6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J |
|
| intravenous |
| whole body |
| 1E12 GC/mouse |
| once |
|
| 150 microliters |
| 28 days |
|
|
|
|
| Measured Values |
| Samples Size: | 4 |
| |
| Mean |
22.19 |
| 1 |
34.53 |
| 2 |
6.8 |
| 3 |
27.46 |
| 4 |
19.96 |
| Mean |
24142.2 |
| 1 |
3977 |
| 3 |
39423 |
| 4 |
39109 |
| 5 |
30239 |
| 6 |
7963 |
| |
| AAV5 heart |
|
|
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging |
|
