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ExperimentAAV Tropism project
Experiment ConditionAAV6 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:brain
Measurement Type:Editing Efficiency
Record ID15000001858

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV6-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 8.24 
1 13.33 
2 10.66 
3 3.08 
4 5.9 
Measurement Units: GC/ug DNA
Mean 14949.83 
1 26528 
2 19532 
3 7840 
4 9037 
5 929 
6 25833 
  
AAV6 brain
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging