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ExperimentAAV Tropism project
Experiment ConditionAAV7 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:heart
Measurement Type:Editing Efficiency
Record ID15000001902

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV7-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 99.02 
1 98.78 
2 98.55 
3 99.19 
4 99.54 
Measurement Units: GC/ug DNA
Mean 146512.5 
1 126383 
2 170264 
3 131074 
4 149803 
5 100055 
6 201496 
  
AAV7 heart
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging