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ExperimentAAV Tropism project
Experiment ConditionAAV7 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:lung
Measurement Type:Editing Efficiency
Record ID15000001906

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV7-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 22.43 
1 17.67 
2 19.74 
3 26.95 
4 25.37 
Measurement Units: GC/ug DNA
Mean 15010.83 
1 7193 
2 18822 
3 21235 
4 14856 
5 18886 
6 9073 
  
AAV7 lung
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging