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ExperimentAAV Tropism project
Experiment ConditionAAV7 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:eye
Measurement Type:Editing Efficiency
Record ID15000001920

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV7-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 25.1 
1 23.7 
2 23.97 
3 34.91 
4 17.8 
Measurement Units: GC/ug DNA
Mean 15773.67 
1 8872 
2 27261 
3 8834 
4 24725 
5 14493 
6 10457 
  
AAV7 eye
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging