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ExperimentAAV Tropism project
Experiment ConditionAAV8 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:lung
Measurement Type:Editing Efficiency
Record ID15000001946

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 53.89 
1 69.42 
2 87.62 
3 12.22 
4 46.29 
Measurement Units: GC/ug DNA
Mean 57680.83 
1 51152 
2 43398 
3 63194 
4 79623 
5 99314 
6 9404 
  
AAV8 lung
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging