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ExperimentAAV Tropism project
Experiment ConditionAAV8 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:skin of body
Measurement Type:Editing Efficiency
Record ID15000001969

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 25.92 
1 20.49 
2 12.74 
3 42.3 
4 28.16 
Measurement Units: GC/ug DNA
Mean 373820.2 
1 179067 
2 158778 
3 181355 
5 358132 
6 991769 
  
AAV8 skin of body
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging