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ExperimentAAV Tropism project
Experiment ConditionAAV9 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:brain
Measurement Type:Editing Efficiency
Record ID15000001998

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAV9-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 8.62 
1 6.31 
2 17.29 
3 7.89 
4 2.98 
Measurement Units: GC/ug DNA
Mean 30779.67 
1 45730 
2 47150 
3 49160 
4 22821 
5 13312 
6 6505 
  
AAV9 brain
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging