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ExperimentAAV Tropism project
Experiment ConditionAAVrh8 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:adrenal gland
Measurement Type:Editing Efficiency
Record ID15000002016

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 96.21 
1 95.52 
2 96.11 
3 97.33 
4 95.88 
Measurement Units: GC/ug DNA
Mean 1424310.33 
1 1262408 
2 2698760 
3 1451457 
4 2650404 
5 252656 
6 230177 
  
AAVrh8 adrenal gland
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging