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ExperimentAAV Tropism project
Experiment ConditionAAVrh8 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:heart
Measurement Type:Editing Efficiency
Record ID15000002022

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 96.09 
1 97.1 
2 93.66 
3 95.33 
4 98.27 
Measurement Units: GC/ug DNA
Mean 461804.5 
1 317898 
2 455716 
3 457516 
4 1064537 
5 198667 
6 276493 
  
AAVrh8 heart
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging