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ExperimentAAV Tropism project
Experiment ConditionAAVrh8 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:liver
Measurement Type:Editing Efficiency
Record ID15000002025

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 98.91 
1 98.27 
2 98.67 
3 99.39 
4 99.32 
Measurement Units: GC/ug DNA
Mean 14399180.4 
1 13562619 
2 26833177 
3 18283639 
5 9202857 
6 4113610 
  
AAVrh8 liver
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging