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ExperimentAAV Tropism project
Experiment ConditionAAVrh8 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:brain
Measurement Type:Editing Efficiency
Record ID15000002038

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 8.77 
1 10.79 
2 8.6 
3 4.52 
4 11.18 
Measurement Units: GC/ug DNA
Mean 7044.6 
1 1498 
2 1534 
3 10146 
4 7419 
5 14626 
  
AAVrh8 brain
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging