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ExperimentAAV Tropism project
Experiment ConditionAAVrh8 females
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:heart
Measurement Type:Editing Efficiency
Record ID15000002042

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh8-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 97.66 
1 99.01 
2 95.65 
3 98.07 
4 97.91 
Measurement Units: GC/ug DNA
Mean 411986 
1 140443 
2 104970 
3 74523 
4 501029 
5 627015 
6 1023936 
  
AAVrh8 heart
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging