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ExperimentAAV Tropism project
Experiment ConditionAAVrh10 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:diaphragm
Measurement Type:Editing Efficiency
Record ID15000002059

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh10-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 87.71 
1 93.95 
2 88.27 
3 82.19 
4 86.43 
Measurement Units: GC/ug DNA
Mean 559028.83 
1 621847 
2 107541 
3 863085 
4 651711 
5 514404 
6 595585 
  
AAVrh10 diaphragm
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging