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ExperimentAAV Tropism project
Experiment ConditionAAVrh10 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:heart
Measurement Type:Editing Efficiency
Record ID15000002062

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh10-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 98.76 
1 98.83 
2 99.23 
3 98.17 
4 98.8 
Measurement Units: GC/ug DNA
Mean 1569452.5 
1 3825927 
2 287165 
3 1839078 
4 1352048 
5 947497 
6 1165000 
  
AAVrh10 heart
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging