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ExperimentAAV Tropism project
Experiment ConditionAAVrh74 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:brain
Measurement Type:Editing Efficiency
Record ID15000002098

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh74-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 15.12 
1 18.23 
2 16.92 
3 16.26 
4 9.08 
Measurement Units: GC/ug DNA
Mean 8839.83 
1 5029 
2 13701 
3 4735 
4 14867 
5 6679 
6 8028 
  
AAVrh74 brain
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging