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ExperimentAAV Tropism project
Experiment ConditionAAVrh74 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:eye
Measurement Type:Editing Efficiency
Record ID15000002100

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh74-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 26.47 
1 12.18 
2 34.01 
3 44.74 
4 14.93 
Measurement Units: GC/ug DNA
Mean 15236 
1 58261 
2 20314 
3 1430 
4 4019 
5 2006 
6 5386 
  
AAVrh74 eye
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging