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ExperimentAAV Tropism project
Experiment ConditionAAVrh74 males
Assay Description: Cre activity was assessed by image quantification
Tissue Measured:lung
Measurement Type:Editing Efficiency
Record ID15000002106

Editor
Delivery SystemAAV
Delivery System SubtypeViral vector
Guide
VectorAAVrh74-ZsGreen-Cre;

Model SpeciesMouse
Model NameB6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J

Application Methodintravenous
Application Sitewhole body
Dosage1E12 GC/mouse
Injection Frequencyonce
Injection Rate
Injection Volume150 microliters
Days post injection28 days
Editor Format
Antidote Id
Antidote Description

Measured Values
Samples Size: 4
 
Replicate Result (Editing Efficiency)
Measurement Units: % cells tdTomato positive
Mean 56.28 
1 65.9 
2 88.87 
3 19.7 
4 50.65 
Measurement Units: GC/ug DNA
Mean 139794.4 
1 121115 
2 444889 
3 9159 
4 82395 
5 41414 
  
AAVrh74 lung
AAV serotypes delivering Cre recombinase were tested by intravenous delivery into Ai9 mice and chacterized by imaging