Delivery System: RNP-NC-no ligand with Lipofectamine 2000
Summary
SCGE ID | 12000000225 |
Name | RNP-NC-no ligand with Lipofectamine 2000 |
Description | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. RNP was combined in various ratios with Lipofectamine 2000 (Thermo, cat# 11668030) to determine a positive control. |
Type | Nanoparticle |
Subtype | polymer-RNP nanocapsule |
Source | Gong Lab |
Nanoparticle Size | 37-38 nm |
Zeta Potential | -0.5 to -1 mV |
Projects & Experiments
This Delivery System: RNP-NC-no ligand with Lipofectamine 2000 is being used ...Project | Initiative | Contact PI | |
---|---|---|---|
|
Collaborative Opportunity Fund |
Ross C. Wilson, PhD
Samira Kiani, PhD
Shaoqin (Sarah) Gong, PhD
(University of Pittsburgh) |