Delivery System: RNP-NC-no ligand with Lipofectamine 2001
Summary
| SCGE ID | 12000000226 |
| Name | RNP-NC-no ligand with Lipofectamine 2001 |
| Description | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. RNP was combined in various ratios with Lipofectamine 2000 (Thermo, cat# 11668030) to determine a positive control. |
| Type | Nanoparticle |
| Subtype | polymer-RNP nanocapsule |
| Source | Gong Lab |
| Nanoparticle Size | 37-38 nm |
| Zeta Potential | -0.5 to -1 mV |
Projects & Experiments
This Delivery System: RNP-NC-no ligand with Lipofectamine 2001 is being used ...| Project | Initiative | Contact PI | |
|---|---|---|---|
| Collaborative Opportunity Fund |
Ross C. Wilson, PhD
Samira Kiani, PhD
Shaoqin (Sarah) Gong, PhD
(University of Pittsburgh) |
|