SCGE ID11000000163
SymbolABE8e-Cas12a
DescriptionA-to-G base editor
SpeciesLachnospiraceae Bacterium
TypeBase Editor (Cas12a)
SubtypeAdenine base editor

ActivityA-to-G base edit
Substratedouble stranded DNA
DSB Cleavage TypeNick
PAM5' TTTV
FusionEvolved adenine base editor (ABE8e)

SourceLiu lab


This Genome Editor: ABE8e-Cas12a is being used ...
Project Initiative Contact PI
Collaborative Opportunity Fund Paul B McCray, Jr, MD Alice F Tarantal, PhD David Guay, PhD David R Liu, PhD
(University of Iowa)
NIH Report