Development System
Mock-Neg Control | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
    
    
    
    
    
        
        
        
        
            
                
                    
                        
                        
                        
                        
                        
                        
                            
                        
                    
                        
                        
                            
                            
                            
                        
    
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            | Comparing CRISPR/Cas9 gene editing efficiencies between AAV9 and AAVcc47 in Ai9 mice with a 1:3 Cas9 to sgRNA ratio (CMV promoter) |  | Mock-Neg Control |  
                | Editing efficiency calculated by counting fluorescent cells (TdTomato) compared to DAPI stained cells. |  
                | heart |  
                | Editing Efficiency |  | 15000001032 |  | 
 |  |  |  |  |  |  |  |  |  |  |  | 
 |  | Mouse |  | B6.Cg-Gt(ROSA)26Sor ^ tm9(CAG-tdTomato)Hze/J |  | 
 |  | intravenous |  | liver and heart |  |  |  |  |  |  |  |  |  | 4 weeks |  |  |  |  |  |  |  | 
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                | Measured Values |  
                | Samples Size: | 2 |  |  |  
                
                
             
                 
                     
                     
                      
                
                | Mean | 0.02  |  
                
                | 1 | 0.039878  |  |  |  | 
    
    
    
        
            
            
                
                | Publication Title | 
            
            
            
                
                    
                    | Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI | 
            
                
                    
                    | Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. NCBI |