Experiment Biomarker assays to evaluate toxicity and inflammation induced by AAVs in ES cell derived kidney organoids. Experiment Condition Control Assay Description: KIM-1 and MCP-1 levels were measured using the Meso Scale Discovery (MSD) platform Tissue Measured: Measurement Type: Biomarker Detection Record ID 15000003424 Editor Delivery System Delivery System Subtype Guide Vector Model Species Human Model Name Human kidney organoid (ESC-derived) Sample Sex Female Application Method control Application Site Dosage control Injection Frequency Injection Rate Injection Volume Days post injection 7 days Editor Format Antidote Id Antidote Description Measured Values Samples Size: 3   Replicate Result (Biomarker Detection) Measurement Units: KIM-1 (pg/mL) Mean 0  1 0  2 0  3 0  Measurement Units: MCP-1 (pg/mL) Mean 453.18  1 493.31  2 656.29  3 209.93