Experiment Biomarker assays to evaluate toxicity induced by AAVs in iPS cell derived kidney organoids. Experiment Condition AAV2/8 Assay Description: KIM-1 levels were measured using the Meso Scale Discovery (MSD) platform Tissue Measured: Measurement Type: Biomarker Detection Record ID 15000003430 Editor Delivery System AAV Delivery System Subtype Viral vector Guide Vector AAV2/8CMVeGFP; Model Species Human Model Name Human kidney organoid (iPSC-derived) Application Method virus Application Site Dosage MOI=10^5 Injection Frequency Injection Rate Injection Volume Days post injection 7 days Editor Format AAV vector encoded Antidote Id Antidote Description Measured Values Samples Size: 3   Replicate Result (Biomarker Detection) Measurement Units: KIM-1 (pg/mL) Mean 30.46  1 41.96  2 22.29  3 27.13