Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells |
FSD323 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000899 |
|
AsCas12a (Feldan Therapeutics) |
FSD323 |
Amphiphilic peptide |
3849 45-5' |
|
|
Human |
Primary Airway Epithelia |
|
|
|
2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
|
|
|
|
ribonucleoprotein (RNP) |
|
|
|
Measured Values |
Samples Size: | 2 |
|
Mean |
21.67  |
1 |
25.27  |
2 |
18.06  |
| |
|