Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells |
FSX7 |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000939 |
|
AsCas12a (Feldan Therapeutics) |
FSX7 |
Amphiphilic peptide |
3849 45-5' |
|
|
Human |
Primary Airway Epithelia |
|
|
|
2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
|
|
|
|
ribonucleoprotein (RNP) |
|
|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
22.93  |
1 |
25.19  |
2 |
24.16  |
3 |
19.44  |
| |
|