Peptide Shuttle optimization to deliver Cas12a RNP to human airway epithelia cells |
S10 Scr. |
Calculated editing efficiency by % of NGS reads that showed an indel |
|
Editing Efficiency |
15000000942 |
|
AsCas12a (Feldan Therapeutics) |
S10 Scr. |
Amphiphilic peptide |
3849 45-5' |
|
|
Human |
Primary Airway Epithelia |
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2uM gRNA, 1.33uM Cas12a, 40uM Shuttle |
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ribonucleoprotein (RNP) |
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Measured Values |
Samples Size: | 3 |
|
Mean |
4.8  |
1 |
4.4  |
2 |
5.5  |
3 |
4.5  |
| |
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