Development System
S10 | SCGE Toolkit
Database of study and experiment data generated by the Somatic Cell Genome Editing Consortium
Gene editing in vitro by various peptide variants delivering Cas12a in NK cells. |
S10 |
Calculated editing efficiency by T7E1 digestion. |
|
Editing Efficiency |
15000000531 |
|
AsCas12a (Feldan Therapeutics) |
S10 |
Amphiphilic peptide |
NKG2A |
|
|
Human |
NK |
|
|
|
1.33uM Cas12a/2.0uM gRNA/7.5uM Shuttle Peptide |
|
|
|
48 hours |
ribonucleoprotein (RNP) |
|
|
|
Measured Values |
Samples Size: | 3 |
|
Mean |
24.99  |
1 |
23.95680  |
2 |
24.02615  |
3 |
26.98109  |
| |
|
Publication Title |
Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. NCBI |